Ethyl 3,4-di-O-benzyl-2-O-(2-tert-butyloxycarbonylethanoyl)-1-thio-α-L-rhamnopyranoside

Base Information

Chemical Name:Ethyl 3,4-di-O-benzyl-2-O-(2-tert-butyloxycarbonylethanoyl)-1-thio-α-L-rhamnopyranoside
CAS No.:172296-77-4
Molecular Formula:C₂₉H₃₈O₇S
Molecular Weight:530.683
Hs Code.:

Synonyms:Ethyl 3,4-di-O-benzyl-2-O-(2-tert-butyloxycarbonylethanoyl)-1-thio-α-L-rhamnopyranoside

Suppliers and Price of Ethyl 3,4-di-O-benzyl-2-O-(2-tert-butyloxycarbonylethanoyl)-1-thio-α-L-rhamnopyranoside

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of Ethyl 3,4-di-O-benzyl-2-O-(2-tert-butyloxycarbonylethanoyl)-1-thio-α-L-rhamnopyranoside

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of Ethyl 3,4-di-O-benzyl-2-O-(2-tert-butyloxycarbonylethanoyl)-1-thio-α-L-rhamnopyranoside

There total 2 articles about Ethyl 3,4-di-O-benzyl-2-O-(2-tert-butyloxycarbonylethanoyl)-1-thio-α-L-rhamnopyranoside which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

: 40052-13-9
mono-tert-butyl malonate

: 130847-19-7
ethyl 3,4-di-O-benzyl-1-thio-α-L-rhamnopyranoside

: 172296-77-4
Ethyl 3,4-di-O-benzyl-2-O-(2-tert-butyloxycarbonylethanoyl)-1-thio-α-L-rhamnopyranoside

Guidance literature:: With dmap; dicyclohexyl-carbodiimide; In dichloromethane; for 3h; Ambient temperature;

Reference yield:

: 132799-03-2
ethyl 4-O-benzyl-1-thio-α-L-rhamnopyranoside

: 172296-77-4
Ethyl 3,4-di-O-benzyl-2-O-(2-tert-butyloxycarbonylethanoyl)-1-thio-α-L-rhamnopyranoside

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) Bu₂SnO, molecular sieves 4 Angstroem, 2.) CsF / 1.) benzene, reflux, 5 h, 2.) DMF, r.t., 2.5 h

2: 70 percent / DCC, DMAP / CH₂Cl₂ / 3 h / Ambient temperature

With dmap; 4 A molecular sieve; di(n-butyl)tin oxide; dicyclohexyl-carbodiimide; cesium fluoride; In dichloromethane;

Reference yield:

: 172296-77-4
Ethyl 3,4-di-O-benzyl-2-O-(2-tert-butyloxycarbonylethanoyl)-1-thio-α-L-rhamnopyranoside

: Benzyl O-(3,4-di-O-benzyl-α-L-rhamnopyranosyl)-(1->4)-2-O-benzoyl-6-O-benzyl-α-D-glucopyranoside 2',3-malonate

Guidance literature:: Multi-step reaction with 4 steps

1: CF₃COOH / CH₂Cl₂ / 24 h / Ambient temperature

2: 62 percent / DCC, DMAP / CH₂Cl₂ / 3 h / Ambient temperature

3: 86 percent / NaCNBH₃, HCl, molecular sieves 3 Angstroem / diethyl ether; tetrahydrofuran / Ambient temperature

4: 30 percent / NIS, TMSOTf, molecular sieves 3 Angstroem / CH₂Cl₂ / 1.) r.t., 1 h, 2.) -55 deg C, 10 min

With hydrogenchloride; dmap; N-iodo-succinimide; trimethylsilyl trifluoromethanesulfonate; 3 A molecular sieve; sodium cyanoborohydride; dicyclohexyl-carbodiimide; trifluoroacetic acid; In tetrahydrofuran; diethyl ether; dichloromethane;