Amino-(4-benzyloxy-phenyl)-acetic acid (1S,2S,4R)-1,3,3-trimethyl-bicyclo[2.2.1]hept-2-yl ester

Base Information

• Chemical Name: Amino-(4-benzyloxy-phenyl)-acetic acid (1S,2S,4R)-1,3,3-trimethyl-bicyclo[2.2.1]hept-2-yl ester
• CAS No.: 115991-61-2
• Molecular Formula: C₂₅H₃₁NO₃
• Molecular Weight: 393.526

Synonyms:Amino-(4-benzyloxy-phenyl)-acetic acid (1S,2S,4R)-1,3,3-trimethyl-bicyclo[2.2.1]hept-2-yl ester

Chemical Property of Amino-(4-benzyloxy-phenyl)-acetic acid (1S,2S,4R)-1,3,3-trimethyl-bicyclo[2.2.1]hept-2-yl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Amino-(4-benzyloxy-phenyl)-acetic acid (1S,2S,4R)-1,3,3-trimethyl-bicyclo[2.2.1]hept-2-yl ester

There total 3 articles about Amino-(4-benzyloxy-phenyl)-acetic acid (1S,2S,4R)-1,3,3-trimethyl-bicyclo[2.2.1]hept-2-yl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(4-Benzyloxy-phenyl)-(2-nitro-phenylsulfanylamino)-acetic acid (1S,2S,4R)-1,3,3-trimethyl-bicyclo[2.2.1]hept-2-yl ester (103300-71-6) → Amino-(4-benzyloxy-phenyl)-acetic acid (1S,2S,4R)-1,3,3-trimethyl-bicyclo[2.2.1]hept-2-yl ester (115991-61-2)

Guidance literature:

With hydrogenchloride; In acetone;

DOI:10.1021/jm00165a027

Reference yield:

D-2-[p-(benzyloxy)phenyl]glycine (69489-40-3) → Amino-(4-benzyloxy-phenyl)-acetic acid (1S,2S,4R)-1,3,3-trimethyl-bicyclo[2.2.1]hept-2-yl ester (115991-61-2)

Guidance literature:

Multi-step reaction with 3 steps

1: 69 percent / 2N NaOH / dioxane / 2 h

2: dicyclohexylcarbodiimide, 4-(dimethylamino)pyridine / CH₂Cl₂ / 1.) -78 deg C, 0.5 h, 2.) -23 deg C

3: 5N HCl / acetone

With hydrogenchloride; dmap; sodium hydroxide; dicyclohexyl-carbodiimide; In 1,4-dioxane; dichloromethane; acetone;

DOI:10.1021/jm00165a027

Reference yield:

(-)-α-fenchol (470-08-6,512-13-0,1632-73-1,2217-02-9,14575-74-7,22627-95-8,36386-49-9,36386-50-2,64439-31-2) → Amino-(4-benzyloxy-phenyl)-acetic acid (1S,2S,4R)-1,3,3-trimethyl-bicyclo[2.2.1]hept-2-yl ester (115991-61-2)

Guidance literature:

Multi-step reaction with 2 steps

1: dicyclohexylcarbodiimide, 4-(dimethylamino)pyridine / CH₂Cl₂ / 1.) -78 deg C, 0.5 h, 2.) -23 deg C

2: 5N HCl / acetone

With hydrogenchloride; dmap; dicyclohexyl-carbodiimide; In dichloromethane; acetone;

DOI:10.1021/jm00165a027

upstream raw materials:

(4-Benzyloxy-phenyl)-(2-nitro-phenylsulfanylamino)-acetic acid (1S,2S,4R)-1,3,3-trimethyl-bicyclo[2.2.1]hept-2-yl ester

D-2-[p-(benzyloxy)phenyl]glycine

(-)-α-fenchol

Downstream raw materials:

(S)-3-Amino-N-[(4-hydroxy-phenyl)-((1S,2S,4R)-1,3,3-trimethyl-bicyclo[2.2.1]hept-2-yloxycarbonyl)-methyl]-succinamic acid

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 115991-61-2 Amino-(4-benzyloxy-phenyl)-acetic acid (1S,2S,4R)-1,3,3-trimethyl-bicyclo[2.2.1]hept-2-yl ester

Send

Send

Metric Ton KG G Pound L ML

Send

Send