Technology Process of 3,17-diethyl-8,12-bis(p-(isobutoxycarbonyl)phenyl)-2,7,13,18-tetramethyl-21H,24H-bilin-1,19-dione
There total 6 articles about 3,17-diethyl-8,12-bis(p-(isobutoxycarbonyl)phenyl)-2,7,13,18-tetramethyl-21H,24H-bilin-1,19-dione which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
formic acid; chloranil;
In
dichloromethane;
for 30h;
Heating;
DOI:10.1021/jo030091t
- Guidance literature:
-
Multi-step reaction with 6 steps
1.1: 94 percent / acetic acid; H2O2; KI / ethanol; H2O / 0.33 h / 75 - 80 °C
2.1: 77 percent / Pd(PPh3)4; Na2CO3 / dimethylformamide; H2O / Heating
3.1: NaOH / ethanol; H2O / 4 h / Heating
4.1: HBr / methanol; H2O / 9 h / Heating
4.2: NaOH / ethanol; H2O / 2 h / Heating
5.1: Cs2CO3 / dimethylformamide / 18 h / 80 °C
6.1: 80 percent / p-chloranil; formic acid / CH2Cl2 / 30 h / Heating
With
sodium hydroxide; tetrakis(triphenylphosphine) palladium(0); formic acid; hydrogen bromide; dihydrogen peroxide; chloranil; sodium carbonate; caesium carbonate; acetic acid; potassium iodide;
In
methanol; ethanol; dichloromethane; water; N,N-dimethyl-formamide;
2.1: Suzuki coupling;
DOI:10.1021/jo030091t
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: 77 percent / Pd(PPh3)4; Na2CO3 / dimethylformamide; H2O / Heating
2.1: NaOH / ethanol; H2O / 4 h / Heating
3.1: HBr / methanol; H2O / 9 h / Heating
3.2: NaOH / ethanol; H2O / 2 h / Heating
4.1: Cs2CO3 / dimethylformamide / 18 h / 80 °C
5.1: 80 percent / p-chloranil; formic acid / CH2Cl2 / 30 h / Heating
With
sodium hydroxide; tetrakis(triphenylphosphine) palladium(0); formic acid; hydrogen bromide; chloranil; sodium carbonate; caesium carbonate;
In
methanol; ethanol; dichloromethane; water; N,N-dimethyl-formamide;
1.1: Suzuki coupling;
DOI:10.1021/jo030091t
