Oxiranecarbonyl chloride, 2-methyl-3-phenyl-, trans- (9CI)

Base Information

• Chemical Name: Oxiranecarbonyl chloride, 2-methyl-3-phenyl-, trans- (9CI)
• CAS No.: 89848-84-0
• Molecular Formula: C₁₀H₉ClO₂
• Molecular Weight: 196.633
• Mol file: 89848-84-0.mol

Synonyms:Oxiranecarbonyl chloride, 2-methyl-3-phenyl-, trans- (9CI)

Chemical Property of Oxiranecarbonyl chloride, 2-methyl-3-phenyl-, trans- (9CI)

Chemical Property:

• PSA: 29.60000
• LogP: 2.28200

Purity/Quality:

98% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Oxiranecarbonyl chloride, 2-methyl-3-phenyl-, trans- (9CI)

There total 1 articles about Oxiranecarbonyl chloride, 2-methyl-3-phenyl-, trans- (9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

Sodium; (2R,3S)-2-methyl-3-phenyl-oxirane-2-carboxylate (53635-54-4) → (2R,3S)-2-Methyl-3-phenyl-oxirane-2-carbonyl chloride (89848-84-0)

Guidance literature:

With pyridine; oxalyl dichloride; In tetrahydrofuran; for 1h; Ambient temperature;

DOI:10.1021/jo00186a030

Reference yield:

(2R,3S)-2-Methyl-3-phenyl-oxirane-2-carbonyl chloride (89848-84-0) → (2R,3S)-2-Methyl-3-phenyl-oxirane-2-carbonyl azide (89848-98-6)

Guidance literature:

With pyridine; hydrogen azide; In diethyl ether; benzene; for 1h; Yield given; -20 to 10 deg C;

DOI:10.1021/jo00186a030

Reference yield:

(2R,3S)-2-Methyl-3-phenyl-oxirane-2-carbonyl chloride (89848-84-0) → 4-methyl-5-phenyl-3H-oxazol-2-one (61416-45-3)

Guidance literature:

Multi-step reaction with 2 steps

1: hydrazoic acid, pyridine / diethyl ether; benzene / 1 h / -20 to 10 deg C

2: 66 percent / benzene / 1 h / Heating

With pyridine; hydrogen azide; In diethyl ether; benzene;

DOI:10.1021/jo00186a030

upstream raw materials:

Sodium; (2R,3S)-2-methyl-3-phenyl-oxirane-2-carboxylate

Downstream raw materials:

(2R,3S)-2-Methyl-3-phenyl-oxirane-2-carbonyl azide

4-methyl-5-phenyl-3H-oxazol-2-one

Refernces