C₃₆H₃₇NO₉

Base Information

• Chemical Name: C₃₆H₃₇NO₉
• CAS No.: 99458-27-2
• Molecular Formula: C₃₆H₃₇NO₉
• Molecular Weight: 627.691
• Mol file: 99458-27-2.mol

Synonyms:C₃₆H₃₇NO₉

Chemical Property of C₃₆H₃₇NO₉

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₃₆H₃₇NO₉

There total 8 articles about C₃₆H₃₇NO₉ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

C42H51NO10Si (99475-54-4) → C36H37NO9 (99458-27-2)

Guidance literature:

With hydrogen fluoride; In acetonitrile; at 20 ℃; for 4h;

DOI:10.1021/jo00351a008

Reference yield:

Methyl (2R,3S)-(+)-2-hydroxy-3-azido-3-phenyl-propionate (99458-15-8) → C36H37NO9 (99458-27-2)

Guidance literature:

Multi-step reaction with 6 steps

1: 94 percent / triethylamine, 4-(dimethylamino)pyridine / CH₂Cl₂ / 1 h

2: 1.) H₂ / 1.) 10percent Pd/C / 1.) CH₃OH, 15 h, 2.) CH₃OH, RT, 72 h

3: 96 percent / ethyldiisopropylamine / CH₂Cl₂ / 40 h

4: 92 percent / potassium carbonate / methanol; H₂O / 15 h

5: 61 percent / 4-(dimethylamino)pyridine, 2-dipyridyl carbonate / CH₂Cl₂ / 20 h / 20 °C

6: 70 percent / 40percent aq. hydrofluoric acid / acetonitrile / 4 h / 20 °C

With dmap; 2,2'-dipyridyl carbonate; hydrogen fluoride; hydrogen; potassium carbonate; triethylamine; N-ethyl-N,N-diisopropylamine; palladium on activated charcoal; In methanol; dichloromethane; water; acetonitrile;

DOI:10.1021/jo00351a008

Reference yield:

(2S,3R)-2,3-epoxy-3-phenylpropan-1-ol (99528-63-9) → C36H37NO9 (99458-27-2)

Guidance literature:

Multi-step reaction with 8 steps

1: 1.) sodium bicarbonate, sodium periodate, ruthenium trichloride trihydrate / 1.) CCl₄, acetonitrile, water, 20 deg C, 44 h, 2.) Et₂O

2: 90 percent / azidotrimethylsilane, zinc chloride / 48 h / 68 °C

3: 94 percent / triethylamine, 4-(dimethylamino)pyridine / CH₂Cl₂ / 1 h

4: 1.) H₂ / 1.) 10percent Pd/C / 1.) CH₃OH, 15 h, 2.) CH₃OH, RT, 72 h

5: 96 percent / ethyldiisopropylamine / CH₂Cl₂ / 40 h

6: 92 percent / potassium carbonate / methanol; H₂O / 15 h

7: 61 percent / 4-(dimethylamino)pyridine, 2-dipyridyl carbonate / CH₂Cl₂ / 20 h / 20 °C

8: 70 percent / 40percent aq. hydrofluoric acid / acetonitrile / 4 h / 20 °C

With dmap; ruthenium trichloride; sodium periodate; 2,2'-dipyridyl carbonate; trimethylsilylazide; hydrogen fluoride; hydrogen; sodium hydrogencarbonate; potassium carbonate; triethylamine; N-ethyl-N,N-diisopropylamine; zinc(II) chloride; palladium on activated charcoal; In methanol; dichloromethane; water; acetonitrile;

DOI:10.1021/jo00351a008

upstream raw materials:

C₄₂H₅₁NO₁₀Si

Methyl (2R,3S)-(+)-2-hydroxy-3-azido-3-phenyl-propionate

methyl (2R,3S)-3-benzoylamino-2-hydroxy-3-phenylpropanoate

(2R,3R)-(+)-methyl 3-phenyloxiranecarboxylate