1-acetoxy-1-(2-naphthyl)-3-phenyl-2-(phenylsulfinyl)-2-propene

Base Information

• Chemical Name: 1-acetoxy-1-(2-naphthyl)-3-phenyl-2-(phenylsulfinyl)-2-propene
• CAS No.: 442160-35-2
• Molecular Formula: C₂₇H₂₂O₃S
• Molecular Weight: 426.536
• Mol file: 442160-35-2.mol

Synonyms:1-acetoxy-1-(2-naphthyl)-3-phenyl-2-(phenylsulfinyl)-2-propene

Chemical Property of 1-acetoxy-1-(2-naphthyl)-3-phenyl-2-(phenylsulfinyl)-2-propene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-acetoxy-1-(2-naphthyl)-3-phenyl-2-(phenylsulfinyl)-2-propene

There total 6 articles about 1-acetoxy-1-(2-naphthyl)-3-phenyl-2-(phenylsulfinyl)-2-propene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

acetic anhydride (108-24-7) + 1-(2-naphthyl)-3-phenyl-2-(phenylsulfinyl)-2-propen-1-ol (442160-34-1) → 1-acetoxy-1-(2-naphthyl)-3-phenyl-2-(phenylsulfinyl)-2-propene (442160-35-2)

Guidance literature:

DOI:10.1016/S0040-4020(02)00151-5

Reference yield:

racemic methyl phenyl sulfoxide (1193-82-4) → 1-acetoxy-1-(2-naphthyl)-3-phenyl-2-(phenylsulfinyl)-2-propene (442160-35-2)

Guidance literature:

Multi-step reaction with 5 steps

1: 91 percent / LDA

2: 98 percent / pyridine; 4-(dimethylamino)pyridine / 30 h / 20 °C

3: 93 percent / sodium hydride / dimethylsulfoxide / 20 °C

4: 95 percent / LDA

With pyridine; dmap; sodium hydride; lithium diisopropyl amide; In dimethyl sulfoxide;

DOI:10.1016/S0040-4020(02)00151-5

Reference yield:

erythro-2-(phenylsulfinyl)-1-phenyl-1-ethanol (49639-26-1) → 1-acetoxy-1-(2-naphthyl)-3-phenyl-2-(phenylsulfinyl)-2-propene (442160-35-2)

Guidance literature:

Multi-step reaction with 4 steps

1: 98 percent / pyridine; 4-(dimethylamino)pyridine / 30 h / 20 °C

2: 93 percent / sodium hydride / dimethylsulfoxide / 20 °C

3: 95 percent / LDA

With pyridine; dmap; sodium hydride; lithium diisopropyl amide; In dimethyl sulfoxide;

DOI:10.1016/S0040-4020(02)00151-5

upstream raw materials:

acetic anhydride

1-(2-naphthyl)-3-phenyl-2-(phenylsulfinyl)-2-propen-1-ol

racemic methyl phenyl sulfoxide

(E)-2-phenyl-1-(phenylsulfinyl)ethene

Downstream raw materials:

2-(3-phenylpropa-1,2-dienyl)naphthalene