1',26-bis-O-(1,1-dimethylethyl)dimethylsilyl-3,5:7,9:11,13-tris-O-(1-methylethylidine)-15-O-triisopropylsiloxy-filipin III

Base Information

• Chemical Name: 1',26-bis-O-(1,1-dimethylethyl)dimethylsilyl-3,5:7,9:11,13-tris-O-(1-methylethylidine)-15-O-triisopropylsiloxy-filipin III
• CAS No.: 198955-38-3
• Molecular Formula: C₆₅H₁₁₈O₁₁Si₃
• Molecular Weight: 1159.9
• Mol file: 198955-38-3.mol

Synonyms:1',26-bis-O-(1,1-dimethylethyl)dimethylsilyl-3,5:7,9:11,13-tris-O-(1-methylethylidine)-15-O-triisopropylsiloxy-filipin III

Chemical Property of 1',26-bis-O-(1,1-dimethylethyl)dimethylsilyl-3,5:7,9:11,13-tris-O-(1-methylethylidine)-15-O-triisopropylsiloxy-filipin III

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1',26-bis-O-(1,1-dimethylethyl)dimethylsilyl-3,5:7,9:11,13-tris-O-(1-methylethylidine)-15-O-triisopropylsiloxy-filipin III

There total 1 articles about 1',26-bis-O-(1,1-dimethylethyl)dimethylsilyl-3,5:7,9:11,13-tris-O-(1-methylethylidine)-15-O-triisopropylsiloxy-filipin III which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

triisopropylsilyl trifluoromethanesulfonate (80522-42-5) + 1',26-bis-O-(1,1-dimethylethyl)dimethylsilyl-3,5:7,9:11,13-tris-O-(1-methylethylidine)filipin III (198955-37-2) → 1',26-bis-O-(1,1-dimethylethyl)dimethylsilyl-3,5:7,9:11,13-tris-O-(1-methylethylidine)-15-O-triisopropylsiloxy-filipin III (198955-38-3)

Guidance literature:

With 2,6-dimethylpyridine; In dichloromethane; at 0 - 20 ℃;

DOI:10.1016/S0040-4020(99)00457-3

Reference yield: 39.0%

1',26-bis-O-(1,1-dimethylethyl)dimethylsilyl-3,5:7,9:11,13-tris-O-(1-methylethylidine)-15-O-triisopropylsiloxy-filipin III (198955-38-3) → 15-Deoxylagosin (480-49-9)

Guidance literature:

1',26-bis-O-(1,1-dimethylethyl)dimethylsilyl-3,5:7,9:11,13-tris-O-(1-methylethylidine)-15-O-triisopropylsiloxy-filipin III; With pyridinium p-toluenesulfonate; In tetrahydrofuran; methanol; ethylene glycol; at 20 - 60 ℃; for 3h;

With pyridine hydrogenfluoride; In tetrahydrofuran; pyridine; at 0 - 20 ℃; for 12h;

DOI:10.1016/S0040-4020(99)00457-3

upstream raw materials:

triisopropylsilyl trifluoromethanesulfonate

1',26-bis-O-(1,1-dimethylethyl)dimethylsilyl-3,5:7,9:11,13-tris-O-(1-methylethylidine)filipin III

Downstream raw materials:

15-Deoxylagosin