Technology Process of 1-(2-Hydroxy-6-methylsulfanyl-phenyl)-3-pentyl-urea
There total 8 articles about 1-(2-Hydroxy-6-methylsulfanyl-phenyl)-3-pentyl-urea which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 7 steps
1: SOCl2
2: 1.) NaN3, 2.) H2O, 4.) NaOH, 5.) HCl
3: 1.) 98percent sulfuric acid, NaNO2, 2.) CuCl2, 36percent aq. HCl / 1.) acetic acid, 10 deg C, 1 h, 2.) acetic acid, RT, 1 h
4: 35 percent / dimethylformamide; H2O / 2 h / 100 °C
5: H2 / 10percent Pd/C / ethyl acetate / 1 h / 760 Torr
6: CHCl3
7: BBr3 / CH2Cl2 / 2 h / Heating
With
hydrogenchloride; sodium hydroxide; thionyl chloride; sodium azide; sulfuric acid; water; hydrogen; boron tribromide; copper dichloride; sodium nitrite;
palladium on activated charcoal;
In
dichloromethane; chloroform; water; ethyl acetate; N,N-dimethyl-formamide;
DOI:10.1021/jm00063a014
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 35 percent / dimethylformamide; H2O / 2 h / 100 °C
2: H2 / 10percent Pd/C / ethyl acetate / 1 h / 760 Torr
3: CHCl3
4: BBr3 / CH2Cl2 / 2 h / Heating
With
hydrogen; boron tribromide;
palladium on activated charcoal;
In
dichloromethane; chloroform; water; ethyl acetate; N,N-dimethyl-formamide;
DOI:10.1021/jm00063a014
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 1.) 98percent sulfuric acid, NaNO2, 2.) CuCl2, 36percent aq. HCl / 1.) acetic acid, 10 deg C, 1 h, 2.) acetic acid, RT, 1 h
2: 35 percent / dimethylformamide; H2O / 2 h / 100 °C
3: H2 / 10percent Pd/C / ethyl acetate / 1 h / 760 Torr
4: CHCl3
5: BBr3 / CH2Cl2 / 2 h / Heating
With
hydrogenchloride; sulfuric acid; hydrogen; boron tribromide; copper dichloride; sodium nitrite;
palladium on activated charcoal;
In
dichloromethane; chloroform; water; ethyl acetate; N,N-dimethyl-formamide;
DOI:10.1021/jm00063a014
