2-Amino-5-bromo-3-(dimethylamino)pyrazine

Base Information

• Chemical Name: 2-Amino-5-bromo-3-(dimethylamino)pyrazine
• CAS No.: 89641-34-9
• Molecular Formula: C₆H₉BrN₄
• Molecular Weight: 217.068
• DSSTox Substance ID: DTXSID50557438
• Wikidata: Q82439336
• Mol file: 89641-34-9.mol

Synonyms:89641-34-9;2-AMINO-5-BROMO-3-(DIMETHYLAMINO)PYRAZINE;6-bromo-N2,N2-dimethylpyrazine-2,3-diamine;5-bromo-3-N,3-N-dimethylpyrazine-2,3-diamine;SCHEMBL7319923;DTXSID50557438;FBHYHUKOQSACFX-UHFFFAOYSA-N;MFCD08460063;AKOS015854872;FS-3290;2-amino-5-bromo-3-dimethylaminopyrazine;CS-0209195;5-Bromo-N~3~,N~3~-dimethylpyrazine-2,3-diamine;A861108;J-507902;6-Bromo-N2 pound notN2-dimethylpyrazine-2 pound not3-diamine

Chemical Property of 2-Amino-5-bromo-3-(dimethylamino)pyrazine

Chemical Property:

• Vapor Pressure: 0.000212mmHg at 25°C
• Refractive Index: 1.656
• Boiling Point: 326.7 °C at 760 mmHg
• Flash Point: 151.4 °C
• PSA: 55.04000
• Density: 1.64 g/cm³
• LogP: 1.46850
• XLogP3: 0.9
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 1
• Exact Mass: 216.00106
• Heavy Atom Count: 11
• Complexity: 130

Purity/Quality:

98%min ^*data from raw suppliers

6-Bromo-N2,N2-dimethylpyrazine-2,3-diamine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CN(C)C1=NC(=CN=C1N)Br

Technology Process of 2-Amino-5-bromo-3-(dimethylamino)pyrazine

There total 3 articles about 2-Amino-5-bromo-3-(dimethylamino)pyrazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-amino-3,5-dibromopyrazine (24241-18-7) → 2-Amino-5-brom-3-dimethylamino-pyrazin (89641-34-9)

Guidance literature:

In ethanol; dimethyl amine;

Reference yield:

aqueous dimethylamine + 2-amino-3,5-dibromopyrazine (24241-18-7) → 2-Amino-5-brom-3-dimethylamino-pyrazin (89641-34-9)

Guidance literature:

Reference yield:

→ 2-Amino-5-brom-3-dimethylamino-pyrazin (89641-34-9)

Guidance literature:

2-Amino-3,5-dibrom-pyrazin, Dimethylamin <10h, 130grad, im Rohr>;

upstream raw materials:

2-amino-3,5-dibromopyrazine

Refernces

• 1、 -. "8-alkylaminoimidazo(1,2-a)pyrazines and derivatives, their preparation and their application in therapy". . . Retrieved 2008/06/13.