2-(2-Chloro-4-iodo-phenylamino)-N-cyclopropylmethoxy-3,4-difluoro-5-dimethylsulfamoyl-benzamide

Base Information

• Chemical Name: 2-(2-Chloro-4-iodo-phenylamino)-N-cyclopropylmethoxy-3,4-difluoro-5-dimethylsulfamoyl-benzamide
• CAS No.: 285125-88-4
• Molecular Formula: C₁₉H₁₉ClF₂IN₃O₄S
• Molecular Weight: 585.798

Synonyms:2-(2-Chloro-4-iodo-phenylamino)-N-cyclopropylmethoxy-3,4-difluoro-5-dimethylsulfamoyl-benzamide

Chemical Property of 2-(2-Chloro-4-iodo-phenylamino)-N-cyclopropylmethoxy-3,4-difluoro-5-dimethylsulfamoyl-benzamide

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Technology Process of 2-(2-Chloro-4-iodo-phenylamino)-N-cyclopropylmethoxy-3,4-difluoro-5-dimethylsulfamoyl-benzamide

There total 1 articles about 2-(2-Chloro-4-iodo-phenylamino)-N-cyclopropylmethoxy-3,4-difluoro-5-dimethylsulfamoyl-benzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 63.0%

dichloromethane-tetrahydrofuran + PD 224339 (285127-13-1) + O-(cyclopropylmethyl)hydroxylamine hydrochloride → 2-(2-Chloro-4-iodo-phenylamino)-N-cyclopropylmethoxy-3,4-difluoro-5-dimethylsulfamoyl-benzamide (285125-88-4)

Guidance literature:

With hydrogenchloride; benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate; N-ethyl-N,N-diisopropylamine;

upstream raw materials:

PD 224339

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