methyl 2,3,6-tri-O-benzyl-α-D-glucopyranoside methyl 4'-O-benzyl-3'-O-trimethylsilyl-1'-thio-α-L-rhamnopyranoside 4-2'-2-naphthylidene acetal

Base Information

• Chemical Name: methyl 2,3,6-tri-O-benzyl-α-D-glucopyranoside methyl 4'-O-benzyl-3'-O-trimethylsilyl-1'-thio-α-L-rhamnopyranoside 4-2'-2-naphthylidene acetal
• CAS No.: 1028832-81-6
• Molecular Formula: C₅₆H₆₆O₁₀SSi
• Molecular Weight: 959.286
• Mol file: 1028832-81-6.mol

Synonyms:methyl 2,3,6-tri-O-benzyl-α-D-glucopyranoside methyl 4'-O-benzyl-3'-O-trimethylsilyl-1'-thio-α-L-rhamnopyranoside 4-2'-2-naphthylidene acetal

Chemical Property of methyl 2,3,6-tri-O-benzyl-α-D-glucopyranoside methyl 4'-O-benzyl-3'-O-trimethylsilyl-1'-thio-α-L-rhamnopyranoside 4-2'-2-naphthylidene acetal

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of methyl 2,3,6-tri-O-benzyl-α-D-glucopyranoside methyl 4'-O-benzyl-3'-O-trimethylsilyl-1'-thio-α-L-rhamnopyranoside 4-2'-2-naphthylidene acetal

There total 1 articles about methyl 2,3,6-tri-O-benzyl-α-D-glucopyranoside methyl 4'-O-benzyl-3'-O-trimethylsilyl-1'-thio-α-L-rhamnopyranoside 4-2'-2-naphthylidene acetal which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

methyl O-2,3,6-tri-O-benzyl-α-D-glucopyranoside (19488-48-3) + methyl 4-O-benzyl-2-O-(2-naphthylmethyl)-3-O-trimethylsilyl-1-thio-α-L-rhamnopyranoside (1028832-75-8) → methyl 2,3,6-tri-O-benzyl-α-D-glucopyranoside methyl 4'-O-benzyl-3'-O-trimethylsilyl-1'-thio-α-L-rhamnopyranoside 4-2'-2-naphthylidene acetal (1028832-81-6)

Guidance literature:

With 4 A molecular sieve; 2,3-dicyano-5,6-dichloro-p-benzoquinone; In dichloromethane; at 0 ℃; for 4h;

DOI:10.1021/ja801574q

Reference yield: 68.0%

methyl 2,3,6-tri-O-benzyl-α-D-glucopyranoside methyl 4'-O-benzyl-3'-O-trimethylsilyl-1'-thio-α-L-rhamnopyranoside 4-2'-2-naphthylidene acetal (1028832-81-6) → methyl 4-O-benzyl-2,3-O-naphthylidene-β-L-rhamnopyranosyl-(1->4)-2,3,6-tri-O-benzyl-α-D-glucopyranoside (1028832-84-9)

Guidance literature:

With 2,6-di-tert-butyl-4-methylpyridine; 4 A molecular sieve; methyl trifluoromethanesulfonate; In 1,2-dichloro-ethane; at 20 ℃; for 48h;

DOI:10.1021/ja801574q

upstream raw materials:

methyl O-2,3,6-tri-O-benzyl-α-D-glucopyranoside

methyl 4-O-benzyl-2-O-(2-naphthylmethyl)-3-O-trimethylsilyl-1-thio-α-L-rhamnopyranoside

Downstream raw materials:

methyl 4-O-benzyl-2,3-O-naphthylidene-β-L-rhamnopyranosyl-(1->4)-2,3,6-tri-O-benzyl-α-D-glucopyranoside