N'-[(1E)-(2-hydroxyphenyl)methylidene]quinoline-2-carbohydrazide

Base Information

• Chemical Name: N'-[(1E)-(2-hydroxyphenyl)methylidene]quinoline-2-carbohydrazide
• CAS No.: 71658-29-2
• Molecular Formula: C₁₇H₁₃N₃O₂
• Molecular Weight: 291.309
• Mol file: 71658-29-2.mol

Synonyms:N'-[(1E)-(2-hydroxyphenyl)methylidene]quinoline-2-carbohydrazide

Chemical Property of N'-[(1E)-(2-hydroxyphenyl)methylidene]quinoline-2-carbohydrazide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N'-[(1E)-(2-hydroxyphenyl)methylidene]quinoline-2-carbohydrazide

There total 9 articles about N'-[(1E)-(2-hydroxyphenyl)methylidene]quinoline-2-carbohydrazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 50.0%

quinoline-2-carboxylic acid hydrazide (5382-44-5) + salicylaldehyde (90-02-8) → N'-[(1E)-(2-hydroxyphenyl)methylidene]quinoline-2-carbohydrazide (71658-29-2)

Guidance literature:

With acetic acid; In water;

DOI:10.1016/j.ejmech.2015.07.018

Reference yield:

quinoline 2-carbaldehyde (5470-96-2) → N'-[(1E)-(2-hydroxyphenyl)methylidene]quinoline-2-carbohydrazide (71658-29-2)

Guidance literature:

Multi-step reaction with 3 steps

1: iodine; potassium hydroxide / 0.25 h / 0 °C

2: hydrazine hydrate / ethanol / 0.5 h / Reflux; Microwave irradiation

3: acetic acid / water

With iodine; hydrazine hydrate; acetic acid; potassium hydroxide; In ethanol; water;

DOI:10.1016/j.ejmech.2015.07.018

Reference yield:

quinoline-2-carboxylic acid methyl ester (19575-07-6) → N'-[(1E)-(2-hydroxyphenyl)methylidene]quinoline-2-carbohydrazide (71658-29-2)

Guidance literature:

Multi-step reaction with 2 steps

1: hydrazine hydrate / ethanol / 0.5 h / Reflux; Microwave irradiation

2: acetic acid / water

With hydrazine hydrate; acetic acid; In ethanol; water;

DOI:10.1016/j.ejmech.2015.07.018

upstream raw materials:

quinoline-2-carboxylic acid hydrazide

salicylaldehyde

2-methyl-benzyl alcohol

quinoline 2-carbaldehyde

Downstream raw materials:

La⁽³⁺⁾*(OCOCH₃)^(1-)*C₉H₆NCONNCHC₆H₄O^(2-) = [La(OCOCH₃)(C₉H₆NCONNCHC₆H₄O)]

Y⁽³⁺⁾*(OCOCH₃)^(1-)*C₉H₆NCONNCHC₆H₄O^(2-) = [Y(OCOCH₃)(C₉H₆NCONNCHC₆H₄O)]

Dy⁽³⁺⁾*(OCOCH₃)^(1-)*C₉H₆NCONNCHC₆H₄O^(2-) = [Dy(OCOCH₃)(C₉H₆NCONNCHC₆H₄O)]

Gd⁽³⁺⁾*(OCOCH₃)^(1-)*C₉H₆NCONNCHC₆H₄O^(2-) = [Gd(OCOCH₃)(C₉H₆NCONNCHC₆H₄O)]