Technology Process of (rac)-1-(2',4'-dimethoxy-6'-hydroxyphenyl)-2-methylanthraquinone
There total 9 articles about (rac)-1-(2',4'-dimethoxy-6'-hydroxyphenyl)-2-methylanthraquinone which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
hydrogen; sodium acetate;
10percent Pd on carbon;
In
methanol;
for 2h;
under 1500.15 Torr;
DOI:10.1021/jo020189s
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: 67 percent / NaH / tetrahydrofuran; CH2Cl2 / 3 h / 20 °C
2.1: PPh3; Pd(OAc)2; NaOAc / 1 h / 60 °C / 0.01 Torr
2.2: 89 percent / N,N-dimethyl-acetamide / 1 h / 120 °C
3.1: 71 percent / LiAlH4 / tetrahydrofuran / 3 h / 0 °C
4.1: polymer-bound PPh3; (CBrCl2)2 / CH2Cl2 / 0.17 h / 20 °C
5.1: 53 percent / H2; NaOAc / 10percent Pd on carbon / methanol / 2 h / 1500.15 Torr
With
palladium diacetate; lithium aluminium tetrahydride; 1,2-dibromo-1,1,2,2-tetrachloroethane; polymer-bound PPh3; hydrogen; sodium acetate; sodium hydride; triphenylphosphine;
10percent Pd on carbon;
In
tetrahydrofuran; methanol; dichloromethane;
DOI:10.1021/jo020189s
- Guidance literature:
-
Multi-step reaction with 6 steps
1.1: (COCl)2; dimethylformamide / CH2Cl2 / 1 h / Heating
2.1: 67 percent / NaH / tetrahydrofuran; CH2Cl2 / 3 h / 20 °C
3.1: PPh3; Pd(OAc)2; NaOAc / 1 h / 60 °C / 0.01 Torr
3.2: 89 percent / N,N-dimethyl-acetamide / 1 h / 120 °C
4.1: 71 percent / LiAlH4 / tetrahydrofuran / 3 h / 0 °C
5.1: polymer-bound PPh3; (CBrCl2)2 / CH2Cl2 / 0.17 h / 20 °C
6.1: 53 percent / H2; NaOAc / 10percent Pd on carbon / methanol / 2 h / 1500.15 Torr
With
palladium diacetate; lithium aluminium tetrahydride; oxalyl dichloride; 1,2-dibromo-1,1,2,2-tetrachloroethane; polymer-bound PPh3; hydrogen; sodium acetate; sodium hydride; N,N-dimethyl-formamide; triphenylphosphine;
10percent Pd on carbon;
In
tetrahydrofuran; methanol; dichloromethane;
DOI:10.1021/jo020189s
