3'-amino-3'-deoxy-3'-(L-2-acetoxy-3-phenylpropionyl)-N⁶,N⁶-dimethyladenosine

Base Information

Chemical Name:3'-amino-3'-deoxy-3'-(L-2-acetoxy-3-phenylpropionyl)-N⁶,N⁶-dimethyladenosine
CAS No.:833447-70-4
Molecular Formula:C₂₃H₂₈N₆O₆
Molecular Weight:484.512
Hs Code.:

3'-amino-3'-deoxy-3'-(L-2-acetoxy-3-phenylpropionyl)-N<sup>6</sup>,N<sup>6</sup>-dimethyladenosine

Synonyms:3'-amino-3'-deoxy-3'-(L-2-acetoxy-3-phenylpropionyl)-N⁶,N⁶-dimethyladenosine

Suppliers and Price of 3'-amino-3'-deoxy-3'-(L-2-acetoxy-3-phenylpropionyl)-N⁶,N⁶-dimethyladenosine

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 3'-amino-3'-deoxy-3'-(L-2-acetoxy-3-phenylpropionyl)-N⁶,N⁶-dimethyladenosine

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Technology Process of 3'-amino-3'-deoxy-3'-(L-2-acetoxy-3-phenylpropionyl)-N⁶,N⁶-dimethyladenosine

There total 2 articles about 3'-amino-3'-deoxy-3'-(L-2-acetoxy-3-phenylpropionyl)-N⁶,N⁶-dimethyladenosine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 73.0%

: 33173-31-8
(S)-3-phenyl-2-acetyloxypropionic acid

: 58-60-6
3'-amino-3'-deoxy-N⁶,N⁶-dimethyladenosine

: 833447-70-4
3'-amino-3'-deoxy-3'-(L-2-acetoxy-3-phenylpropionyl)-N⁶,N⁶-dimethyladenosine

Guidance literature:: With 1-hydroxy-pyrrolidine-2,5-dione; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In N,N-dimethyl-formamide; at 0 - 20 ℃;
DOI:10.1016/j.tet.2004.10.023

Reference yield:

: 20312-36-1
L-3-phenyllactic acid

: 833447-70-4
3'-amino-3'-deoxy-3'-(L-2-acetoxy-3-phenylpropionyl)-N⁶,N⁶-dimethyladenosine

Guidance literature:: Multi-step reaction with 2 steps

1: pyridine / 24 h / 20 °C

2: 73 percent / EDCI; N-hydroxysuccinimide / dimethylformamide / 0 - 20 °C

With pyridine; 1-hydroxy-pyrrolidine-2,5-dione; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In N,N-dimethyl-formamide;
DOI:10.1016/j.tet.2004.10.023