4-Methylbenzenesulfonic acid 2-[1-(3-bromophenyl)ethylidene]hydrazide

Base Information

Chemical Name:4-Methylbenzenesulfonic acid 2-[1-(3-bromophenyl)ethylidene]hydrazide
CAS No.:75230-52-3
Molecular Formula:C₁₅H₁₅BrN₂O₂S
Molecular Weight:367.266
Hs Code.:
DSSTox Substance ID:DTXSID701156524

Synonyms:DTXSID701156524;D86580;4-Methylbenzenesulfonic acid 2-[1-(3-bromophenyl)ethylidene]hydrazide

Suppliers and Price of 4-Methylbenzenesulfonic acid 2-[1-(3-bromophenyl)ethylidene]hydrazide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of 4-Methylbenzenesulfonic acid 2-[1-(3-bromophenyl)ethylidene]hydrazide

Chemical Property:

XLogP3:3.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:366.00376
Heavy Atom Count:21
Complexity:465

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC1=CC=C(C=C1)S(=O)(=O)NN=C(C)C2=CC(=CC=C2)Br

Technology Process of 4-Methylbenzenesulfonic acid 2-[1-(3-bromophenyl)ethylidene]hydrazide

There total 1 articles about 4-Methylbenzenesulfonic acid 2-[1-(3-bromophenyl)ethylidene]hydrazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 98-59-9
p-toluenesulfonyl chloride

: 75230-52-3
N'-(1-(3-bromophenyl)ethylidene)-4-methylbenzenesulfonohydrazide

Guidance literature:: Multi-step reaction with 2 steps

1: hydrazine hydrate / water; tetrahydrofuran / 0.5 h / 0 °C

2: methanol / Reflux

With hydrazine hydrate; In tetrahydrofuran; methanol; water;
DOI:10.1039/c5cc07833d

Reference yield: 96.0%

: 75230-52-3
N'-(1-(3-bromophenyl)ethylidene)-4-methylbenzenesulfonohydrazide

: 434-45-7
2,2,2-Trifluoroacetophenone

: trans-2-(3-bromophenyl)-2-methyl-3-phenyl-3-(trifluoromethyl)oxirane

Guidance literature:: N'-(1-(3-bromophenyl)ethylidene)-4-methylbenzenesulfonohydrazide; With caesium carbonate; In toluene; at 25 ℃; for 1h; Sealed tube;

2,2,2-Trifluoroacetophenone; With N-benzyl-N,N,N-triethylammonium chloride; In toluene; at 90 ℃; for 12h; diastereoselective reaction; Sealed tube;
DOI:10.1021/acs.orglett.6b01824

Reference yield: 92.0%

: 120-72-9
indole

: 75230-52-3
N'-(1-(3-bromophenyl)ethylidene)-4-methylbenzenesulfonohydrazide

: 1440537-88-1
1-(1-(3-bromophenyl)vinyl)-1H-indole

Guidance literature:: With bis-triphenylphosphine-palladium(II) chloride; oxygen; lithium tert-butoxide; In N,N-dimethyl-formamide; at 80 ℃; for 7h;
DOI:10.1021/ol401217h