3,4,5-tri-O-benzyl-2,6-di-O-(2,3,4,6-tetra-O-benzyl-α-D-mannopyranosyl)-1-O-(1,2-di-O-hexadecanoyl-sn-glycero-3-O-benzylphosphono)-D-myo-inositol

Base Information

• Chemical Name: 3,4,5-tri-O-benzyl-2,6-di-O-(2,3,4,6-tetra-O-benzyl-α-D-mannopyranosyl)-1-O-(1,2-di-O-hexadecanoyl-sn-glycero-3-O-benzylphosphono)-D-myo-inositol
• CAS No.: 916600-12-9
• Molecular Formula: C₁₃₇H₁₇₁O₂₃P
• Molecular Weight: 2216.82
• Mol file: 916600-12-9.mol

Synonyms:3,4,5-tri-O-benzyl-2,6-di-O-(2,3,4,6-tetra-O-benzyl-α-D-mannopyranosyl)-1-O-(1,2-di-O-hexadecanoyl-sn-glycero-3-O-benzylphosphono)-D-myo-inositol

Chemical Property of 3,4,5-tri-O-benzyl-2,6-di-O-(2,3,4,6-tetra-O-benzyl-α-D-mannopyranosyl)-1-O-(1,2-di-O-hexadecanoyl-sn-glycero-3-O-benzylphosphono)-D-myo-inositol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3,4,5-tri-O-benzyl-2,6-di-O-(2,3,4,6-tetra-O-benzyl-α-D-mannopyranosyl)-1-O-(1,2-di-O-hexadecanoyl-sn-glycero-3-O-benzylphosphono)-D-myo-inositol

There total 1 articles about 3,4,5-tri-O-benzyl-2,6-di-O-(2,3,4,6-tetra-O-benzyl-α-D-mannopyranosyl)-1-O-(1,2-di-O-hexadecanoyl-sn-glycero-3-O-benzylphosphono)-D-myo-inositol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 67.0%

(+)-benzyloxy(N,N-diisopropylamino)(1,2-di-O-hexadecanoyl-sn-glycer-3-yl)phosphine (120595-85-9,196304-47-9) + (2,3,4,6-tetra-O-benzyl-α-D-mannopyranosyl)-(1->6)-2-O-(2,3,4,6-tetra-O-benzyl-α-D-mannopyranosyl)-3,4,5-tri-O-benzyl-D-myo-inositol (143994-68-7) → 3,4,5-tri-O-benzyl-2,6-di-O-(2,3,4,6-tetra-O-benzyl-α-D-mannopyranosyl)-1-O-(1,2-di-O-hexadecanoyl-sn-glycero-3-O-benzylphosphono)-D-myo-inositol (916600-12-9)

Guidance literature:

(+)-benzyloxy(N,N-diisopropylamino)(1,2-di-O-hexadecanoyl-sn-glycer-3-yl)phosphine; (2,3,4,6-tetra-O-benzyl-α-D-mannopyranosyl)-(1->6)-2-O-(2,3,4,6-tetra-O-benzyl-α-D-mannopyranosyl)-3,4,5-tri-O-benzyl-D-myo-inositol; With 1H-tetrazole; In dichloromethane; at 20 ℃; for 2h;

With 3-chloro-benzenecarboperoxoic acid; In dichloromethane; at -40 - 20 ℃; for 2h; Further stages.;

DOI:10.1016/j.bmc.2006.07.003

Reference yield: 24.0%

3,4,5-tri-O-benzyl-2,6-di-O-(2,3,4,6-tetra-O-benzyl-α-D-mannopyranosyl)-1-O-(1,2-di-O-hexadecanoyl-sn-glycero-3-O-benzylphosphono)-D-myo-inositol (916600-12-9) → 2,6-di-O-(α-D-mannopyranosyl)-1-O-(1-O-hexadecanoyl-sn-glycero-3-phosphono)-D-myo-inositol

Guidance literature:

With hydrogen; palladium hydroxide - carbon; In methanol; chloroform; water; at 20 ℃; for 10h;

DOI:10.1016/j.bmc.2006.07.003

Reference yield:

3,4,5-tri-O-benzyl-2,6-di-O-(2,3,4,6-tetra-O-benzyl-α-D-mannopyranosyl)-1-O-(1,2-di-O-hexadecanoyl-sn-glycero-3-O-benzylphosphono)-D-myo-inositol (916600-12-9) → 2,6-di-O-(α-D-mannopyranosyl)-1-O-(1,2-di-O-hexadecanoyl-sn-glycero-3-phosphono)-D-myo-inositol

Guidance literature:

With hydrogen; palladium hydroxide - carbon; In tetrahydrofuran; methanol; at 20 ℃; for 2.5h;

DOI:10.1016/j.bmc.2006.07.003

upstream raw materials:

(+)-benzyloxy(N,N-diisopropylamino)(1,2-di-O-hexadecanoyl-sn-glycer-3-yl)phosphine

(2,3,4,6-tetra-O-benzyl-α-D-mannopyranosyl)-(1->6)-2-O-(2,3,4,6-tetra-O-benzyl-α-D-mannopyranosyl)-3,4,5-tri-O-benzyl-D-myo-inositol