Boc-D-Ala-Phe-Gly-1-aminoadamantane

Base Information

Chemical Name:Boc-D-Ala-Phe-Gly-1-aminoadamantane
CAS No.:89662-00-0
Molecular Formula:C₂₉H₄₂N₄O₅
Molecular Weight:526.676
Hs Code.:

Synonyms:Boc-D-Ala-Phe-Gly-1-aminoadamantane

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of Boc-D-Ala-Phe-Gly-1-aminoadamantane

Chemical Property:

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Technology Process of Boc-D-Ala-Phe-Gly-1-aminoadamantane

There total 1 articles about Boc-D-Ala-Phe-Gly-1-aminoadamantane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

: 3744-87-4,7764-95-6,15761-38-3
Boc-(R)-Ala

: 89661-91-6
(S)-N-(Adamantan-1-ylcarbamoylmethyl)-2-amino-3-phenyl-propionamide; compound with trifluoro-acetic acid

: 89662-00-0
Boc-D-Ala-Phe-Gly-1-aminoadamantane

Guidance literature:: With 4-methyl-morpholine; isobutyl chloroformate; In tetrahydrofuran; 1.) 30 min, -10 deg C, 2.) 3 h, room temperature;

Reference yield:

: 89662-00-0
Boc-D-Ala-Phe-Gly-1-aminoadamantane

: 83579-08-2
H-Tyr-D-Ala-Phe-Gly-NH-Ad

Guidance literature:: Multi-step reaction with 3 steps

1: aqueous 90percent trifluoroacetic acid / 0.67 h / Ambient temperature

2: 80 percent / triethylamine / dimethylformamide / 1.) 24 h, 5 deg C, 2.) 24 h, room temperature

3: aqueous 90percent trifluoroacetic acid, anisole / 0.5 h

With methoxybenzene; triethylamine; trifluoroacetic acid; In N,N-dimethyl-formamide;

Reference yield:

: 89662-00-0
Boc-D-Ala-Phe-Gly-1-aminoadamantane

: 89661-85-8
[(S)-1-((R)-1-{(S)-1-[(Adamantan-1-ylcarbamoylmethyl)-carbamoyl]-2-phenyl-ethylcarbamoyl}-ethylcarbamoyl)-2-(4-hydroxy-phenyl)-ethyl]-carbamic acid tert-butyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: aqueous 90percent trifluoroacetic acid / 0.67 h / Ambient temperature

2: 80 percent / triethylamine / dimethylformamide / 1.) 24 h, 5 deg C, 2.) 24 h, room temperature

With triethylamine; trifluoroacetic acid; In N,N-dimethyl-formamide;