Technology Process of N-benzenesulfonyl-2,4-dibromopyrrole
There total 2 articles about N-benzenesulfonyl-2,4-dibromopyrrole which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
N-benzenesulfonyl-2,5-dibromopyrrole;
With
trifluorormethanesulfonic acid;
In
toluene;
at 0 ℃;
for 1h;
Inert atmosphere;
With
triethylamine;
In
toluene;
at 0 - 20 ℃;
for 24h;
Inert atmosphere;
DOI:10.3987/COM-12-S(N)81
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: N-Bromosuccinimide / N,N-dimethyl-formamide / 0.5 h / 20 °C
2.1: trifluorormethanesulfonic acid / toluene / 1 h / 0 °C / Inert atmosphere
2.2: 24 h / 0 - 20 °C / Inert atmosphere
With
N-Bromosuccinimide; trifluorormethanesulfonic acid;
In
N,N-dimethyl-formamide; toluene;
DOI:10.3987/COM-12-S(N)81
- Guidance literature:
-
N-benzenesulfonyl-2,4-dibromopyrrole;
With
n-butyllithium;
In
tetrahydrofuran; hexane;
at -78 ℃;
Inert atmosphere;
methyl chloroformate;
In
tetrahydrofuran; hexane;
at -78 ℃;
regioselective reaction;
DOI:10.1021/ol100810c
