4-(2-Piperidin-1-yl-ethoxy)-benzoic acid

Base Information

Chemical Name:4-(2-Piperidin-1-yl-ethoxy)-benzoic acid
CAS No.:89407-98-7
Molecular Formula:C14H19 N O3
Molecular Weight:249.31
Hs Code.:2933399090
European Community (EC) Number:691-839-7
DSSTox Substance ID:DTXSID40420889
Nikkaji Number:J292.572I
ChEMBL ID:CHEMBL3580432
Mol file:89407-98-7.mol

Synonyms:4-(2-Piperidin-1-yl-ethoxy)-benzoic acid;89407-98-7;4-(2-(Piperidin-1-yl)ethoxy)benzoic acid;4-(2-piperidin-1-ylethoxy)benzoic acid;4-[2-(piperidin-1-yl)ethoxy]benzoic acid;BENZOIC ACID,4-[2-(1-PIPERIDINYL)ETHOXY]-;SR-01000945173;4-(2-piperidinoethoxy)benzoic acid;Benzoic acid, 4-[2-(1-piperidinyl)ethoxy]-;SCHEMBL1027972;CHEMBL3580432;DTXSID40420889;4-(2-piperidino ethoxy)benzoic acid;BBL012629;MFCD01871351;STK744312;AKOS000103057;4-(2-piperidin-1-ylmethoxy)benzoic acid;VS-03420;BB 0217869;FT-0731346;A50710;SR-01000945173-1;SR-01000945173-2

Suppliers and Price of 4-(2-Piperidin-1-yl-ethoxy)-benzoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

SynChem
4-(2-Piperidin-1-yl-ethoxy)-benzoic acid 95+%
1 g
$ 225.00

SynChem
4-(2-Piperidin-1-yl-ethoxy)-benzoic acid 95+%
5 g
$ 675.00

Matrix Scientific
4-(2-Piperidin-1-yl-ethoxy)-benzoic acid
1g
$ 495.00

Crysdot
4-(2-(Piperidin-1-yl)ethoxy)benzoicacid 95+%
1g
$ 374.00

American Custom Chemicals Corporation
4-(2-PIPERIDIN-1-YL-ETHOXY)-BENZOIC ACID 95.00%
500MG
$ 777.32

AK Scientific
4-(2-Piperidin-1-yl-ethoxy)-benzoicacid
5g
$ 2176.00

Acrotein
4-(2-Piperidin-1-yl-ethoxy)-benzoicacid 97%
5g
$ 79.93

Acrotein
4-(2-Piperidin-1-yl-ethoxy)-benzoicacid 97%
1g
$ 26.58

Total 27 raw suppliers

Chemical Property of 4-(2-Piperidin-1-yl-ethoxy)-benzoic acid

Chemical Property:

Boiling Point:413.2±25.0 °C(Predicted)
PKA:4.37±0.10(Predicted)
PSA：49.77000
Density:1.154±0.06 g/cm3(Predicted)
LogP:2.18740
XLogP3:0
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:5
Exact Mass:249.13649347
Heavy Atom Count:18
Complexity:256

Purity/Quality:

99%, ^*data from raw suppliers

4-(2-Piperidin-1-yl-ethoxy)-benzoic acid 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CCN(CC1)CCOC2=CC=C(C=C2)C(=O)O

Technology Process of 4-(2-Piperidin-1-yl-ethoxy)-benzoic acid

There total 6 articles about 4-(2-Piperidin-1-yl-ethoxy)-benzoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.6%

: 89407-97-6
4-[2-(N-piperidine)-ethoxy]benzoic acid methyl ester

: 89407-98-7
4-(2-(piperidin-1-yl)-ethoxy)benzoic acid

Guidance literature:: With sodium hydroxide; In tetrahydrofuran; at 50 ℃; for 10h;

Reference yield: 84.0%

: 93148-78-8
ethyl 4-(2-Piperidinylethoxy)benzoate

: 89407-98-7
4-(2-(piperidin-1-yl)-ethoxy)benzoic acid

Guidance literature:: ethyl 4-(2-Piperidinylethoxy)benzoate; With sodium hydroxide; In methanol; at 20 ℃; for 15h;

With hydrogenchloride; In methanol; water;
DOI:10.1021/jm200370y

Reference yield:

: 99-76-3,156291-94-0
methyl 4-hydroxylbenzoate

: 89407-98-7
4-(2-(piperidin-1-yl)-ethoxy)benzoic acid

Guidance literature:: Multi-step reaction with 2 steps

1: K₂CO₃ / dimethylformamide / 1.5 h / 100 °C

2: 5 N aq. NaOH / methanol / 48 h

With sodium hydroxide; potassium carbonate; In methanol; N,N-dimethyl-formamide;
DOI:10.1021/jm00374a021