C₁₄H₂₅BrO₃Si

Base Information

• Chemical Name: C₁₄H₂₅BrO₃Si
• CAS No.: 1259475-96-1
• Molecular Formula: C₁₄H₂₅BrO₃Si
• Molecular Weight: 349.34
• Mol file: 1259475-96-1.mol

Synonyms:C₁₄H₂₅BrO₃Si

Chemical Property of C₁₄H₂₅BrO₃Si

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

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Technology Process of C₁₄H₂₅BrO₃Si

There total 3 articles about C₁₄H₂₅BrO₃Si which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 46.0%

1,2-bis(trimethylsiloxy)cyclobutene (17082-61-0) + α-bromocyclohexanone dimethyl ketal (1728-17-2) → C14H25BrO3Si (1259475-96-1)

Guidance literature:

With boron trifluoride diethyl etherate; In dichloromethane; at -78 - 20 ℃; Inert atmosphere;

DOI:10.1139/V10-097

Reference yield:

2-bromocyclohexanone (1056477-06-5,822-85-5) → C14H25BrO3Si (1259475-96-1)

Guidance literature:

Multi-step reaction with 2 steps

1: methanol; toluene-4-sulfonic acid / Inert atmosphere

2: boron trifluoride diethyl etherate / dichloromethane / -78 - 20 °C / Inert atmosphere

With methanol; boron trifluoride diethyl etherate; toluene-4-sulfonic acid; In dichloromethane; 2: Mukaiyama reaction;

DOI:10.1139/V10-097

Reference yield:

2-bromo-cyclohexanol (24796-87-0,5537-67-7) → C14H25BrO3Si (1259475-96-1)

Guidance literature:

Multi-step reaction with 3 steps

1: pyridinium chlorochromate / Inert atmosphere

2: methanol; toluene-4-sulfonic acid / Inert atmosphere

3: boron trifluoride diethyl etherate / dichloromethane / -78 - 20 °C / Inert atmosphere

With methanol; boron trifluoride diethyl etherate; toluene-4-sulfonic acid; pyridinium chlorochromate; In dichloromethane; 3: Mukaiyama reaction;

DOI:10.1139/V10-097

upstream raw materials:

2-bromocyclohexanone

1,2-bis(trimethylsiloxy)cyclobutene

α-bromocyclohexanone dimethyl ketal

2-bromo-cyclohexanol

Refernces