3-Amino-4,5-dichloropyridine

Base Information

• Chemical Name: 3-Amino-4,5-dichloropyridine
• CAS No.: 89284-39-9
• Molecular Formula: C5H4 Cl2 N2
• Molecular Weight: 163.006
• Hs Code.: 2933399090
• Mol file: 89284-39-9.mol

Synonyms:Pyridine,3-amino-4,5-dichloro- (7CI); 3-Amino-4,5-dichloropyridine

Chemical Property of 3-Amino-4,5-dichloropyridine

Chemical Property:

• PSA: 38.91000
• LogP: 2.55180
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C

Purity/Quality:

99% ^*data from raw suppliers

4,5-Dichloropyridin-3-amine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-Amino-4,5-dichloropyridine

There total 1 articles about 3-Amino-4,5-dichloropyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-hydroxy-3-nitropyridine (5435-54-1) → 4,5-dichloro-pyridin-3-ylamine (89284-39-9)

Guidance literature:

Multi-step reaction with 3 steps

1: 95 percent / chlorine (gas); aq. acetic acid / 0.33 h / 20 °C

2: 94 percent / POCl₃ / dimethylformamide / 0.5 h / 120 °C

3: 85 percent / aq. HCl; SnCl₂ / diethyl ether / 2 h / 20 °C

With hydrogenchloride; chlorine; acetic acid; tin(ll) chloride; trichlorophosphate; In diethyl ether; N,N-dimethyl-formamide;

DOI:10.1021/jm051146h

upstream raw materials:

4-hydroxy-3-nitropyridine

Refernces