(3-chloropyrazin-2-yl)methanol

Base Information

• Chemical Name: (3-chloropyrazin-2-yl)methanol
• CAS No.: 89283-32-9
• Molecular Formula: C₅H₅ClN₂O
• Molecular Weight: 144.56
• Hs Code.: 2933990090
• Mol file: 89283-32-9.mol

Synonyms:Pyrazinemethanol,3-chloro- (7CI,9CI); (3-Chloropyrazin-2-yl)methanol

Chemical Property of (3-chloropyrazin-2-yl)methanol

Chemical Property:

• Vapor Pressure: 0.008mmHg at 25°C
• Refractive Index: 1.579
• Boiling Point: 256℃
• Flash Point: 108℃
• PSA: 46.01000
• Density: 1.422
• LogP: 0.62230
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C

Purity/Quality:

97% ^*data from raw suppliers

(3-Chloropyrazin-2-yl)methanol ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: (3-Chloropyrazin-2-yl)methanol (cas# 89283-32-9) is a useful reagent for the preparation of indazolylquinazolinones as inhibitors of human immunodeficiency virus replication.

Technology Process of (3-chloropyrazin-2-yl)methanol

There total 5 articles about (3-chloropyrazin-2-yl)methanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 31.0%

3-chloropyrazine-2-carboxylic acid (27398-39-6) → (3-chloropyrazin-2-yl)methanol (89283-32-9)

Guidance literature:

3-chloropyrazine-2-carboxylic acid; With triethylamine; methyl chloroformate; In tetrahydrofuran; for 0.5h; Cooling with ice;

With sodium tetrahydroborate; In tetrahydrofuran; water; for 1h; Cooling with ice;

Reference yield: 22.0%

methyl chloroformate (79-22-1) + 3-chloropyrazine-2-carboxylic acid (27398-39-6) → (3-chloropyrazin-2-yl)methanol (89283-32-9)

Guidance literature:

methyl chloroformate; 3-chloropyrazine-2-carboxylic acid; With triethylamine; In tetrahydrofuran; at 0 ℃; for 0.166667h;

With sodium tetrahydroborate; In tetrahydrofuran; water; at 0 ℃; for 1h;

Reference yield:

3-chloro-2-pyrazinecarboxaldehyde (121246-96-6) → (3-chloropyrazin-2-yl)methanol (89283-32-9)

Guidance literature:

With sodium tetrahydroborate; In methanol; at 20 ℃; for 1h;

upstream raw materials:

3-chloropyrazine-2-carboxylic acid

3-chloro-2-pyrazinecarboxaldehyde

methyl chloroformate

2-chloropyrazin

Downstream raw materials:

2-chloro-3-(chloromethyl)pyrazine

2-((3-chloropyrazin-2-yl)methyl)isoindoline-1,3-dione

(3-chloro-pyrazin-2-yl)-methylamine

8-chloro-1-iodo-3-isopropylimidazo[1,5-a]pyrazine

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 89283-32-9 (3-chloropyrazin-2-yl)methanol

Send

Send

Metric Ton KG G Pound L ML

Send

Send