Methyl [methyl(diphenyl)silyl]acetate

Base Information

Chemical Name:Methyl [methyl(diphenyl)silyl]acetate
CAS No.:89266-73-9
Molecular Formula:C₁₆H₁₈O₂Si
Molecular Weight:270.403
Hs Code.:
DSSTox Substance ID:DTXSID10700948
Nikkaji Number:J408.710K
Wikidata:Q82632470
Mol file:89266-73-9.mol

Synonyms:Methyl [methyl(diphenyl)silyl]acetate;89266-73-9;methyl 2-[methyl(diphenyl)silyl]acetate;DTXSID10700948;[Diphenyl(methyl)silyl]acetic acid methyl ester

Suppliers and Price of Methyl [methyl(diphenyl)silyl]acetate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of Methyl [methyl(diphenyl)silyl]acetate

Chemical Property:

Vapor Pressure:1.71E-05mmHg at 25°C
Boiling Point:364.2°C at 760 mmHg
Flash Point:174.1°C
PSA：26.30000
Density:1.08 g/mL at 25 °C(lit.)
LogP:2.05240
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:5
Exact Mass:270.107606347
Heavy Atom Count:19
Complexity:273

Purity/Quality:: 95% ^*data from raw suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi
Statements: 36/37/38
Safety Statements: 26-37/39

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC(=O)C[Si](C)(C1=CC=CC=C1)C2=CC=CC=C2
Physical properties clear to light yellow liquids.
Uses vinyl 1,1-dication synthetic equivalent in reactions with Grignard reagents; reagent for Peterson synthesis of α,β-un saturated esters.

Technology Process of Methyl [methyl(diphenyl)silyl]acetate

There total 1 articles about Methyl [methyl(diphenyl)silyl]acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.0%

: 144-79-6
chloromethyldiphenylsilane

: 96-32-2
bromoacetic acid methyl ester

: 89266-73-9
methyl 2-(methyldiphenylsilyl)acetate

Guidance literature:: With iodine; zinc; In diethyl ether; benzene; for 1.5h; Heating;
DOI:10.1002/hlca.19830660725

Reference yield:

: 930-30-3
cyclopent-2-enone

: 7348-78-9
(Z)-1-bromo-2-pentene

: 89266-73-9
methyl 2-(methyldiphenylsilyl)acetate

: methyl trans-2-<3-oxo-2-<(Z)-2-pentenyl>cyclopentyl>-2-(methyldiphenylsilyl)acetate

Guidance literature:: With N,N,N,N,N,N-hexamethylphosphoric triamide; n-butyllithium; diisopropylamine; Yield given. Multistep reaction; 1.) hexane, THF, 10 min, 0 deg C, 3 min -20 deg C; 2.) hexane, THF, -20 deg C, 1 h; 3.) hexane, THF, -40 deg C, 1 h;
DOI:10.1002/hlca.19830660725