5-(2-(3-chloro-4-methoxyphenyl)propan-2-yl)-1-(4-fluorophenyl)-1H-imidazole-2(3H)-thione

Base Information

Chemical Name:5-(2-(3-chloro-4-methoxyphenyl)propan-2-yl)-1-(4-fluorophenyl)-1H-imidazole-2(3H)-thione
CAS No.:1239963-86-0
Molecular Formula:C₁₉H₁₈ClFN₂OS
Molecular Weight:376.882
Hs Code.:

Synonyms:5-(2-(3-chloro-4-methoxyphenyl)propan-2-yl)-1-(4-fluorophenyl)-1H-imidazole-2(3H)-thione

Suppliers and Price of 5-(2-(3-chloro-4-methoxyphenyl)propan-2-yl)-1-(4-fluorophenyl)-1H-imidazole-2(3H)-thione

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 5-(2-(3-chloro-4-methoxyphenyl)propan-2-yl)-1-(4-fluorophenyl)-1H-imidazole-2(3H)-thione

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Technology Process of 5-(2-(3-chloro-4-methoxyphenyl)propan-2-yl)-1-(4-fluorophenyl)-1H-imidazole-2(3H)-thione

There total 1 articles about 5-(2-(3-chloro-4-methoxyphenyl)propan-2-yl)-1-(4-fluorophenyl)-1H-imidazole-2(3H)-thione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1239963-86-0
5-(2-(3-chloro-4-methoxyphenyl)propan-2-yl)-1-(4-fluorophenyl)-1H-imidazole-2-thiol

Guidance literature:

Reference yield: 60.0%

: 99613-64-6
5-(bromomethyl)-2-chlorobenzonitrile

: 1239963-86-0
5-(2-(3-chloro-4-methoxyphenyl)propan-2-yl)-1-(4-fluorophenyl)-1H-imidazole-2(3H)-thione

: 1239956-66-1
2-chloro-5-((5-(2-(3-chloro-4-methoxyphenyl)propan-2-yl)-1-(4-fluorophenyl)-1H-imidazol-2-ylthio)methyl)benzonitrile

Guidance literature:: With potassium carbonate; In acetone; at 20 ℃; for 2h;

Reference yield:

: 99613-64-6
5-(bromomethyl)-2-chlorobenzonitrile

: 1239963-86-0
5-(2-(3-chloro-4-methoxyphenyl)propan-2-yl)-1-(4-fluorophenyl)-1H-imidazole-2(3H)-thione

: 1239956-69-4
5-(2-chloro-5-((5-(2-(3-chloro-4-methoxyphenyl)propan-2-yl)-1-(4-fluorophenyl)-1H-imidazol-2-ylthio)methyl)phenyl)-1H-tetrazole

Guidance literature:: Multi-step reaction with 2 steps

1: potassium carbonate / acetone / 2 h / 20 °C

2: sodium azide; ammonium chloride / N,N-dimethyl-formamide / 16 h / 110 °C

With sodium azide; potassium carbonate; ammonium chloride; In N,N-dimethyl-formamide; acetone;