3-(4-CHLOROPHENYL)PROPYLAMINE HYDROCHLORIDE

Base Information

• Chemical Name: 3-(4-CHLOROPHENYL)PROPYLAMINE HYDROCHLORIDE
• CAS No.: 377084-66-7
• Molecular Formula: C₉H₁₂ClN*ClH
• Molecular Weight: 206.115
• Mol file: 377084-66-7.mol

Synonyms:3-(4-Chlorophenyl)-1-propylamine hydrochloride

Chemical Property of 3-(4-CHLOROPHENYL)PROPYLAMINE HYDROCHLORIDE

Chemical Property:

Purity/Quality:

99% ^*data from raw suppliers

3-(4-chlorophenyl)propan-1-aminehydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-(4-CHLOROPHENYL)PROPYLAMINE HYDROCHLORIDE

There total 1 articles about 3-(4-CHLOROPHENYL)PROPYLAMINE HYDROCHLORIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ 3-(4-Chlorophenyl)-1-propylamine hydrochloride (377084-66-7)

Guidance literature:

Reference yield: 35.0%

piperonal (120-57-0,30024-74-9) + 3-(4-Chlorophenyl)-1-propylamine hydrochloride (377084-66-7) → N-(1,3-benzodioxol-5-ylmethyl)-3-(4-chlorophenyl)propan-1-amine

Guidance literature:

piperonal; 3-(4-Chlorophenyl)-1-propylamine hydrochloride; With triethylamine; In dichloromethane; at 25 ℃; Molecular sieve;

With sodium tris(acetoxy)borohydride; In dichloromethane; at 25 ℃;

DOI:10.1021/acs.jmedchem.6b01881

Reference yield: 24.0%

6-(cyclohexanone-4-yl)benzoxazolin-2-one (377083-54-0) + 3-(4-Chlorophenyl)-1-propylamine hydrochloride (377084-66-7) → 6-{trans-4-[3-(4-chlorophenyl)propylamino]cyclohexyl}-3H-benzoxazol-2-one

Guidance literature:

6-(cyclohexanone-4-yl)benzoxazolin-2-one; 3-(4-Chlorophenyl)-1-propylamine hydrochloride; With 3 A molecular sieve; triethylamine; In tetrahydrofuran; isopropyl alcohol; at 20 ℃; for 2.25h;

With sodium tetrahydroborate; In tetrahydrofuran; isopropyl alcohol; for 12h;

Refernces