(S)-2-(((tert-butoxycarbonyl)amino)(4-chlorophenyl)methyl)acrylic acid

Base Information

• Chemical Name: (S)-2-(((tert-butoxycarbonyl)amino)(4-chlorophenyl)methyl)acrylic acid
• CAS No.: 1385032-47-2
• Molecular Formula: C₁₅H₁₈ClNO₄
• Molecular Weight: 311.765

Synonyms:(S)-2-(((tert-butoxycarbonyl)amino)(4-chlorophenyl)methyl)acrylic acid

Chemical Property of (S)-2-(((tert-butoxycarbonyl)amino)(4-chlorophenyl)methyl)acrylic acid

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (S)-2-(((tert-butoxycarbonyl)amino)(4-chlorophenyl)methyl)acrylic acid

There total 2 articles about (S)-2-(((tert-butoxycarbonyl)amino)(4-chlorophenyl)methyl)acrylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

(S)-methyl 2-((tert-butoxycarbonyl)(4-chlorophenyl)methyl)acrylate (1186668-63-2) → (S)-2-(((tert-butoxycarbonyl)amino)(4-chlorophenyl)methyl)acrylic acid (1385032-47-2)

Guidance literature:

With water; lithium hydroxide; In tetrahydrofuran; at 0 - 20 ℃; for 12h;

DOI:10.1021/jm300664y

Reference yield:

C20H26ClN2O6P (1385032-54-1) → (S)-2-(((tert-butoxycarbonyl)amino)(4-chlorophenyl)methyl)acrylic acid (1385032-47-2)

Guidance literature:

Multi-step reaction with 2 steps

1.1: methanol / tetrahydrofuran / 0.5 h / -15 °C

1.2: 8 h / -15 °C

2.1: water; lithium hydroxide / tetrahydrofuran / 12 h / 0 - 20 °C

With methanol; water; lithium hydroxide; In tetrahydrofuran;

DOI:10.1021/jm300664y

Reference yield:

(S)-2-(((tert-butoxycarbonyl)amino)(4-chlorophenyl)methyl)acrylic acid (1385032-47-2) → C10H10ClNO2 (1385032-64-3)

Guidance literature:

With hydrogenchloride; In ethyl acetate; at 20 ℃; for 2h;

DOI:10.1021/jm300664y

upstream raw materials:

(S)-methyl 2-((tert-butoxycarbonyl)(4-chlorophenyl)methyl)acrylate

C₂₀H₂₆ClN₂O₆P

Downstream raw materials:

C₁₀H₁₀ClNO₂

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 1385032-47-2 (S)-2-(((tert-butoxycarbonyl)amino)(4-chlorophenyl)methyl)acrylic acid

Send

Send

Metric Ton KG G Pound L ML

Send

Send