6-methyl-4,9- diphenyl-2-tosyl-2,3-dihydro-1H-benzo[f]isoindole

Base Information

• Chemical Name: 6-methyl-4,9- diphenyl-2-tosyl-2,3-dihydro-1H-benzo[f]isoindole
• CAS No.: 1260246-19-2
• Molecular Formula: C₃₂H₂₇NO₂S
• Molecular Weight: 489.638
• Mol file: 1260246-19-2.mol

Synonyms:6-methyl-4,9- diphenyl-2-tosyl-2,3-dihydro-1H-benzo[f]isoindole

Chemical Property of 6-methyl-4,9- diphenyl-2-tosyl-2,3-dihydro-1H-benzo[f]isoindole

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of 6-methyl-4,9- diphenyl-2-tosyl-2,3-dihydro-1H-benzo[f]isoindole

There total 2 articles about 6-methyl-4,9- diphenyl-2-tosyl-2,3-dihydro-1H-benzo[f]isoindole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 45.0%

4-methyl-N,N-bis(3-phenylprop-2-yn-1-yl)benzenesulfonamide + para-bromotoluene (106-38-7) → 6-methyl-4,9- diphenyl-2-tosyl-2,3-dihydro-1H-benzo[f]isoindole (1260246-19-2)

Guidance literature:

With tributyl-amine; palladium diacetate; triphenylphosphine; In N,N-dimethyl-formamide; at 20 ℃; Inert atmosphere; Heating;

DOI:10.1055/s-0030-1257908

Reference yield:

4-methyl-N,N-bis(3-phenylprop-2-yn-1-yl)benzenesulfonamide + p-Toluic acid (99-94-5) → 6-methyl-4,9- diphenyl-2-tosyl-2,3-dihydro-1H-benzo[f]isoindole (1260246-19-2) + 8-methyl-4,5-diphenyl-2-tosyl-2,3-dihydro-1H-benzo[e]isoindole

Guidance literature:

With dichloro[1,3-di(ethoxycarbonyl)-2,4,5-trimethylcyclopentadienyl]rhodium(III) dimer; silver(I) acetate; copper(II) acetate monohydrate; In dichloromethane; at 60 ℃; for 24h; Overall yield = 61 %; Overall yield = 29.7 mg; Schlenk technique; Sealed tube;

DOI:10.1002/chem.201901050

upstream raw materials:

para-bromotoluene

p-Toluic acid