1-(3-Bromoprop-1-en-2-yl)-4-chlorobenzene

Base Information

• Chemical Name: 1-(3-Bromoprop-1-en-2-yl)-4-chlorobenzene
• CAS No.: 89220-51-9
• Molecular Formula: C9H8 Br Cl
• Molecular Weight: 231.52
• Hs Code.: 2903999090
• DSSTox Substance ID: DTXSID70460197
• Nikkaji Number: J1.695.281H
• Wikidata: Q82284162
• Mol file: 89220-51-9.mol

Synonyms:89220-51-9;1-(3-Bromoprop-1-en-2-yl)-4-chlorobenzene;1-[1-(bromomethyl)ethenyl]-4-chlorobenzene;SCHEMBL991358;4-chloro-alpha-bromomethylstyrene;DTXSID70460197;p-chloro-alpha-bromomethyl styrene;WLHYINHUIIECRI-UHFFFAOYSA-N;AKOS015965991;EN300-1898370;(3R,4R)-BENZYL4-(TERT-BUTOXYCARBONYLAMINO)-3-HYDROXYPIPERIDINE-1-CARBOXYLATE

Chemical Property of 1-(3-Bromoprop-1-en-2-yl)-4-chlorobenzene

Chemical Property:

• PSA: 0.00000
• LogP: 3.74810
• XLogP3: 4.1
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 0
• Rotatable Bond Count: 2
• Exact Mass: 229.94979
• Heavy Atom Count: 11
• Complexity: 137

Purity/Quality:

98% ^*data from raw suppliers

1-(1-BROMOMETHYL-VINYL)-4-CHLORO-BENZENE 95 ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C=C(CBr)C1=CC=C(C=C1)Cl

Technology Process of 1-(3-Bromoprop-1-en-2-yl)-4-chlorobenzene

There total 7 articles about 1-(3-Bromoprop-1-en-2-yl)-4-chlorobenzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

2-(4-chlorophenyl)-3-hydroxypropene (45941-96-6) → α-bromomethyl-4-chlorostyrene (89220-51-9)

Guidance literature:

2-(4-chlorophenyl)-3-hydroxypropene; With triphenylphosphine; In dichloromethane; at 0 ℃; for 0.166667h;

With carbon tetrabromide; In dichloromethane; at 0 ℃; for 3h;

DOI:10.1002/chem.201300189

Reference yield: 88.0%

1-chloro-4-(1-methylethenyl)-benzene (1712-70-5) → α-bromomethyl-4-chlorostyrene (89220-51-9)

Guidance literature:

With N-Bromosuccinimide; toluene-4-sulfonic acid; In tetrahydrofuran; at 80 ℃; for 4h;

DOI:10.1002/adsc.201700124

Reference yield: 19.0%

1-chloro-4-(1-methylethenyl)-benzene (1712-70-5) → α-bromomethyl-4-chlorostyrene (89220-51-9) + 1-[(1E)-1-bromoprop-1-en-2-yl]-4-chlorobenzene (145949-81-1)

Guidance literature:

With N-Bromosuccinimide; In chlorobenzene; at 132 ℃; for 0.25h;

DOI:10.1080/00397919308009826

upstream raw materials:

1-chloro-4-(1-methylethenyl)-benzene

para-chloroacetophenone

water

2-(4-chlorophenyl)-3-hydroxypropene

Downstream raw materials:

N-<2-(4-chlorophenyl)prop-2-enyl>phthalimide

<2-(4-chlorophenyl)prop-2-enyl>amine

N-tert-butoxycarbonyl-N'-[2-(4-chlorophenyl)allyl]hydrazine

(2R,3S)-5-(4-chlorophenyl)hex-5-ene-1,2,3-triol