1-(4-Methoxy-phenyl)-10H-9-thia-3,4a-diaza-phenanthren-2-one

Base Information

• Chemical Name: 1-(4-Methoxy-phenyl)-10H-9-thia-3,4a-diaza-phenanthren-2-one
• CAS No.: 107174-11-8
• Molecular Formula: C₁₈H₁₄N₂O₂S
• Molecular Weight: 322.387
• Mol file: 107174-11-8.mol

Synonyms:1-(4-Methoxy-phenyl)-10H-9-thia-3,4a-diaza-phenanthren-2-one

Chemical Property of 1-(4-Methoxy-phenyl)-10H-9-thia-3,4a-diaza-phenanthren-2-one

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-(4-Methoxy-phenyl)-10H-9-thia-3,4a-diaza-phenanthren-2-one

There total 2 articles about 1-(4-Methoxy-phenyl)-10H-9-thia-3,4a-diaza-phenanthren-2-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 66.0%

2-(2H-1,4-benzothiazin-3(4H)-ylidene)-2-(4-methoxyphenyl)acetamide (84590-85-2) + N,N-dimethylformamide diethyl diacetal (1188-33-6) → 1-(4-Methoxy-phenyl)-10H-9-thia-3,4a-diaza-phenanthren-2-one (107174-11-8)

Guidance literature:

In N,N-dimethyl-formamide; at 95 ℃; for 2.5h;

DOI:10.1021/jo00383a044

Reference yield:

(2H-1,4-benzothiazin-3(4H)-ylidene)(4-methoxyphenyl)acetonitrile (84590-82-9) → 1-(4-Methoxy-phenyl)-10H-9-thia-3,4a-diaza-phenanthren-2-one (107174-11-8)

Guidance literature:

Multi-step reaction with 2 steps

1: 58 percent / conc. H₂SO₄, HOAc / 5 h / Ambient temperature

2: 66 percent / dimethylformamide / 2.5 h / 95 °C

With sulfuric acid; acetic acid; In N,N-dimethyl-formamide;

DOI:10.1021/jo00383a044

Reference yield:

1-(4-Methoxy-phenyl)-10H-9-thia-3,4a-diaza-phenanthren-2-one (107174-11-8) → 4-(4-methoxyphenyl)-5H-pyrido<3,4-b><1,4>benzothiazin-3-2H-one (84590-88-5)

Guidance literature:

Multi-step reaction with 2 steps

1: dimethylformamide / 55 - 60 °C

2: H₂O / dimethylformamide / 6 h / Heating

With water; In N,N-dimethyl-formamide;

DOI:10.1021/jo00383a044

upstream raw materials:

2-(2H-1,4-benzothiazin-3(4H)-ylidene)-2-(4-methoxyphenyl)acetamide

N,N-dimethylformamide diethyl diacetal

(2H-1,4-benzothiazin-3(4H)-ylidene)(4-methoxyphenyl)acetonitrile

Downstream raw materials:

4-(4-methoxyphenyl)-5H-pyrido<3,4-b><1,4>benzothiazin-3-2H-one