Technology Process of (E)-4-Benzenesulfonyl-2-oxo-2,3,4,5,8,9-hexahydro-oxonine-4-carboxylic acid methyl ester
There total 7 articles about (E)-4-Benzenesulfonyl-2-oxo-2,3,4,5,8,9-hexahydro-oxonine-4-carboxylic acid methyl ester which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 95 percent / pyridine / CH2Cl2; diethyl ether / 0.33 h / 0 °C
2: dimethylformamide / 0.67 h / 0 °C
3: sodium hydride / tetrakis(triphenylphosphine)palladium(0) / mulistep reaction; influence of ligand added (1,2-bis(diphenylphosphino)ethane)
With
pyridine; sodium hydride;
tetrakis(triphenylphosphine) palladium(0);
In
diethyl ether; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1021/ja00534a030
- Guidance literature:
-
Multi-step reaction with 5 steps
1: pyridine / CH2Cl2 / 0 °C
2: perchloric acid / tetrahydrofuran; H2O / Ambient temperature
3: 95 percent / pyridine / CH2Cl2; diethyl ether / 0.33 h / 0 °C
4: dimethylformamide / 0.67 h / 0 °C
5: sodium hydride / tetrakis(triphenylphosphine)palladium(0) / mulistep reaction; influence of ligand added (1,2-bis(diphenylphosphino)ethane)
With
pyridine; perchloric acid; sodium hydride;
tetrakis(triphenylphosphine) palladium(0);
In
tetrahydrofuran; diethyl ether; dichloromethane; water; N,N-dimethyl-formamide;
DOI:10.1021/ja00534a030
- Guidance literature:
-
Multi-step reaction with 2 steps
1: dimethylformamide / 0.67 h / 0 °C
2: sodium hydride / tetrakis(triphenylphosphine)palladium(0) / mulistep reaction; influence of ligand added (1,2-bis(diphenylphosphino)ethane)
With
sodium hydride;
tetrakis(triphenylphosphine) palladium(0);
In
N,N-dimethyl-formamide;
DOI:10.1021/ja00534a030
