(3R,4R,2'S)-trans-N-<1-<2-(propionyloxy)-2-phenylethyl>-3-methyl-4-piperidyl>-N-phenylpropanamide

Base Information

Chemical Name:(3R,4R,2'S)-trans-N-<1-<2-(propionyloxy)-2-phenylethyl>-3-methyl-4-piperidyl>-N-phenylpropanamide
CAS No.:166768-23-6
Molecular Formula:C₂₆H₃₄N₂O₃
Molecular Weight:422.568
Hs Code.:

Synonyms:(3R,4R,2'S)-trans-N-<1-<2-(propionyloxy)-2-phenylethyl>-3-methyl-4-piperidyl>-N-phenylpropanamide

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Chemical Property of (3R,4R,2'S)-trans-N-<1-<2-(propionyloxy)-2-phenylethyl>-3-methyl-4-piperidyl>-N-phenylpropanamide

Chemical Property:

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Technology Process of (3R,4R,2'S)-trans-N-<1-<2-(propionyloxy)-2-phenylethyl>-3-methyl-4-piperidyl>-N-phenylpropanamide

There total 3 articles about (3R,4R,2'S)-trans-N-<1-<2-(propionyloxy)-2-phenylethyl>-3-methyl-4-piperidyl>-N-phenylpropanamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 58329-00-3
1-benzyl-3-methyl-N-phenyl-4-piperidinamine

: 166768-23-6
(3R,4R,2'S)-trans-N-<1-<2-(propionyloxy)-2-phenylethyl>-3-methyl-4-piperidyl>-N-phenylpropanamide

Guidance literature:: Multi-step reaction with 4 steps

1: 8.9 g / H₂ / 10percent Pd/C / ethanol / 6 h / 60 °C / 775.7 Torr

3: 79 percent / 1 h / 100 °C

4: toluene / 5 h / Heating

With hydrogen; palladium on activated charcoal; In ethanol; toluene;
DOI:10.1021/jm00018a026

Reference yield:

: 57444-99-2
trans-3-Methyl-N-phenyl-4-piperidineamine

: 166768-23-6
(3R,4R,2'S)-trans-N-<1-<2-(propionyloxy)-2-phenylethyl>-3-methyl-4-piperidyl>-N-phenylpropanamide

Guidance literature:: Multi-step reaction with 3 steps

2: 79 percent / 1 h / 100 °C

3: toluene / 5 h / Heating

In toluene;
DOI:10.1021/jm00018a026

Reference yield:

: 120143-74-0
(3R,4R)-(-)-trans-3-methyl-N-phenyl-4-piperidinamine

: 166768-23-6
(3R,4R,2'S)-trans-N-<1-<2-(propionyloxy)-2-phenylethyl>-3-methyl-4-piperidyl>-N-phenylpropanamide

Guidance literature:: Multi-step reaction with 2 steps

1: 79 percent / 1 h / 100 °C

2: toluene / 5 h / Heating

In toluene;
DOI:10.1021/jm00018a026