Technology Process of (+/-)-3-hydroxybakuchiol
There total 5 articles about (+/-)-3-hydroxybakuchiol which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
aluminium trichloride; 2,3-Dimethylaniline;
In
dichloromethane;
for 0.5h;
DOI:10.1021/jo0259459
- Guidance literature:
-
Multi-step reaction with 3 steps
1: lithium; 1-(dimethylamino)naphthalene; potassium hydride / potassium acetate / tetrahydrofuran / 3 h / -78 °C
2: 186 mg / acetic acid / tetrahydrofuran / 8 h / -78 - 60 °C
3: 75 percent / dimethylaniline; AlCl3 / CH2Cl2 / 0.5 h
With
aluminium trichloride; N,N-dimethyl-1-naphthalenamine; lithium; potassium hydride; acetic acid; 2,3-Dimethylaniline;
potassium acetate;
In
tetrahydrofuran; dichloromethane;
DOI:10.1021/jo0259459
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 89 percent / [1,2-bis(diphenylphosphino)ethane]dichloroiron(II) / 1,2-dichloro-ethane; hexane / 1 h / Heating
2: lithium; 1-(dimethylamino)naphthalene; potassium hydride / potassium acetate / tetrahydrofuran / 3 h / -78 °C
3: 186 mg / acetic acid / tetrahydrofuran / 8 h / -78 - 60 °C
4: 75 percent / dimethylaniline; AlCl3 / CH2Cl2 / 0.5 h
With
aluminium trichloride; N,N-dimethyl-1-naphthalenamine; {1,2-bis(diphenylphosphino)ethane}dichloroiron; lithium; potassium hydride; acetic acid; 2,3-Dimethylaniline;
potassium acetate;
In
tetrahydrofuran; hexane; dichloromethane; 1,2-dichloro-ethane;
1: Kirmse reaction;
DOI:10.1021/jo0259459
