benzyl 6-O-[2-(2,2,2-trichloroethoxycarbonylamino)-2,4-dideoxy-4-fluoro-3,6-di-O-acetyl-β-D-glucopyranosyl]-2-acetamido-2-deoxy-3-O-acetyl-α-D-galactopyranoside

Base Information

• Chemical Name: benzyl 6-O-[2-(2,2,2-trichloroethoxycarbonylamino)-2,4-dideoxy-4-fluoro-3,6-di-O-acetyl-β-D-glucopyranosyl]-2-acetamido-2-deoxy-3-O-acetyl-α-D-galactopyranoside
• CAS No.: 1193357-25-3
• Molecular Formula: C₃₀H₃₈Cl₃FN₂O₁₄
• Molecular Weight: 775.994
• Mol file: 1193357-25-3.mol

Synonyms:benzyl 6-O-[2-(2,2,2-trichloroethoxycarbonylamino)-2,4-dideoxy-4-fluoro-3,6-di-O-acetyl-β-D-glucopyranosyl]-2-acetamido-2-deoxy-3-O-acetyl-α-D-galactopyranoside

Chemical Property of benzyl 6-O-[2-(2,2,2-trichloroethoxycarbonylamino)-2,4-dideoxy-4-fluoro-3,6-di-O-acetyl-β-D-glucopyranosyl]-2-acetamido-2-deoxy-3-O-acetyl-α-D-galactopyranoside

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of benzyl 6-O-[2-(2,2,2-trichloroethoxycarbonylamino)-2,4-dideoxy-4-fluoro-3,6-di-O-acetyl-β-D-glucopyranosyl]-2-acetamido-2-deoxy-3-O-acetyl-α-D-galactopyranoside

There total 1 articles about benzyl 6-O-[2-(2,2,2-trichloroethoxycarbonylamino)-2,4-dideoxy-4-fluoro-3,6-di-O-acetyl-β-D-glucopyranosyl]-2-acetamido-2-deoxy-3-O-acetyl-α-D-galactopyranoside which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

benzyl 2-acetamido-3-O-acetyl-2-deoxy-α-D-galactopyranoside (3554-95-8) + 2-(2,2,2-trichloroethoxycarbonylamino)-2,4-dideoxy-4-fluoro-3,6-di-O-acetyl-β-D-glucopyranosyl trichloroacetimidate (1193357-13-9) → benzyl 6-O-[2-(2,2,2-trichloroethoxycarbonylamino)-2,4-dideoxy-4-fluoro-3,6-di-O-acetyl-β-D-glucopyranosyl]-2-acetamido-2-deoxy-3-O-acetyl-α-D-galactopyranoside (1193357-25-3)

Guidance literature:

With trimethylsilyl trifluoromethanesulfonate; In dichloromethane; at -70 - -65 ℃; Molecular sieve; Inert atmosphere;

DOI:10.1016/j.tet.2009.07.089

Reference yield:

benzyl 6-O-[2-(2,2,2-trichloroethoxycarbonylamino)-2,4-dideoxy-4-fluoro-3,6-di-O-acetyl-β-D-glucopyranosyl]-2-acetamido-2-deoxy-3-O-acetyl-α-D-galactopyranoside (1193357-25-3) → C27H37FN2O12

Guidance literature:

With acetic acid; cadmium; In N,N-dimethyl-formamide; at 20 ℃; Inert atmosphere;

DOI:10.1016/j.tet.2009.07.089

upstream raw materials:

benzyl 2-acetamido-3-O-acetyl-2-deoxy-α-D-galactopyranoside

2-(2,2,2-trichloroethoxycarbonylamino)-2,4-dideoxy-4-fluoro-3,6-di-O-acetyl-β-D-glucopyranosyl trichloroacetimidate