(5S)-5-Phenyl-2-morpholinone hydrochloride

Base Information

• Chemical Name: (5S)-5-Phenyl-2-morpholinone hydrochloride
• CAS No.: 491833-36-4
• Molecular Formula: C₁₀H₁₁NO₂*ClH
• Molecular Weight: 213.664
• Mol file: 491833-36-4.mol

Synonyms:(S)-5-phenylmorpholin-2-one hydrochloride

Chemical Property of (5S)-5-Phenyl-2-morpholinone hydrochloride

Chemical Property:

• Storage Temp.: Sealed in dry,Room Temperature

Purity/Quality:

99%, ^*data from raw suppliers

(5S)-5-Phenylmorpholin-2-oneHydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Uses: (5S)-5-Phenylmorpholin-2-one Hydrochloride is a building block used in various synthetic preparations. It was used as a reactant in the preparation of enantiopure D-amino acids using Mannich-type reaction of phenylmorpholinone as a chiral amine template.

Technology Process of (5S)-5-Phenyl-2-morpholinone hydrochloride

There total 2 articles about (5S)-5-Phenyl-2-morpholinone hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 53.0%

phenyl 2-bromoacetate (620-72-4) + (2S)-2-phenylglycinol (20989-17-7) → (S)-5-phenylmorpholin-2-one hydrochloride (491833-36-4)

Guidance literature:

phenyl 2-bromoacetate; (2S)-2-phenylglycinol; With N-ethyl-N,N-diisopropylamine; In acetonitrile; at 5 - 20 ℃; for 4.5h;

With hydrogenchloride; In ethyl acetate; at 15 ℃; for 0.333333h; pH=< 2;

Reference yield:

S-(+)-2-phenyl glycinol + phenyl 2-bromoacetate (620-72-4) → (S)-5-phenylmorpholin-2-one hydrochloride (491833-36-4)

Guidance literature:

With N-ethyl-N,N-diisopropylamine; In ethyl acetate; acetonitrile;

Reference yield: 86.0%

(S)-5-phenylmorpholin-2-one hydrochloride (491833-36-4) → (5S)-5-phenylmorpholin-2-one (144896-92-4,134872-85-8)

Guidance literature:

With sodium hydrogencarbonate; In ethyl acetate; for 0.5h;

upstream raw materials:

phenyl 2-bromoacetate

(2S)-2-phenylglycinol

Downstream raw materials:

(1R,3S,5S,8aS)-1,3-bis(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-5-phenyltetrahydro-3H,8H-oxazolo[4,3-c][1 ,4]oxazin-8-one

(5S)-5-phenylmorpholin-2-one

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 491833-36-4 (5S)-5-Phenyl-2-morpholinone hydrochloride

Send

Send

Metric Ton KG G Pound L ML

Send

Send