di(tert-butyl)((2-[(diisopropylphosphino)methyl]phenyl)methyl)phosphine-borane (1/2)

Base Information

• Chemical Name: di(tert-butyl)((2-[(diisopropylphosphino)methyl]phenyl)methyl)phosphine-borane (1/2)
• CAS No.: 914102-11-7
• Molecular Formula: C₂₂H₄₆B₂P₂
• Molecular Weight: 394.177
• Mol file: 914102-11-7.mol

Synonyms:di(tert-butyl)((2-[(diisopropylphosphino)methyl]phenyl)methyl)phosphine-borane (1/2)

Chemical Property of di(tert-butyl)((2-[(diisopropylphosphino)methyl]phenyl)methyl)phosphine-borane (1/2)

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of di(tert-butyl)((2-[(diisopropylphosphino)methyl]phenyl)methyl)phosphine-borane (1/2)

There total 3 articles about di(tert-butyl)((2-[(diisopropylphosphino)methyl]phenyl)methyl)phosphine-borane (1/2) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

n-butyllithium (109-72-8,29786-93-4) + di-tert-butylphosphine borane (128363-76-8) + bisisopropylphosphine-borane complex (119186-85-5) + 1,5-dihydro-benzo[e][1,3,2]dioxathiepine 3,3-dioxide (187879-67-0) → di(tert-butyl)((2-[(diisopropylphosphino)methyl]phenyl)methyl)phosphine-borane (1/2) (914102-11-7)

Guidance literature:

In tetrahydrofuran; hexane; C4H9Li/hexane added to H3BP(C(CH3)3)2H/THF at 0°C, warmed to roomtemp., added to S compd./THF at -78°C, warmed to room temp., sti rred for 30 min, H3BP(CH(CH3)2)2H/C4H9Li/THF/hexane added at -78°C, stirred for 3 h at room temp.; H2O added, extd. (Et2O), the combined org. phase washed (H2O, brine), dried (MgSO4), evapd., recrystd. (hexane); elem. anal.;

DOI:10.1002/hlca.200690174

Reference yield:

di-tert-butylphosphine borane (128363-76-8) + bisisopropylphosphine-borane complex (119186-85-5) + 1,5-dihydro-benzo[e][1,3,2]dioxathiepine 3,3-dioxide (187879-67-0) → di(tert-butyl)((2-[(diisopropylphosphino)methyl]phenyl)methyl)phosphine-borane (1/2) (914102-11-7)

Guidance literature:

With n-butyllithium; In tetrahydrofuran; hexanes; at -78 - 20 ℃;

Reference yield:

di(tert-butyl)chlorophosphine (13716-10-4) → di(tert-butyl)((2-[(diisopropylphosphino)methyl]phenyl)methyl)phosphine-borane (1/2) (914102-11-7)

Guidance literature:

Multi-step reaction with 2 steps

1: N,N-dimethyl-formamide

2: hexane; tetrahydrofuran

In tetrahydrofuran; hexane; N,N-dimethyl-formamide;

DOI:10.1002/hlca.200690174

upstream raw materials:

n-butyllithium

di-tert-butylphosphine borane

bisisopropylphosphine-borane complex

1,5-dihydro-benzo[e][1,3,2]dioxathiepine 3,3-dioxide