2-bromo-1-[4-(1-methyl-5-trifluoromethyl-1H-pyrazol-3-yl)-phenyl]-ethanone

Base Information

Chemical Name:2-bromo-1-[4-(1-methyl-5-trifluoromethyl-1H-pyrazol-3-yl)-phenyl]-ethanone
CAS No.:929899-17-2
Molecular Formula:C₁₃H₁₀BrF₃N₂O
Molecular Weight:347.134
Hs Code.:

Synonyms:2-bromo-1-[4-(1-methyl-5-trifluoromethyl-1H-pyrazol-3-yl)-phenyl]-ethanone

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 2-bromo-1-[4-(1-methyl-5-trifluoromethyl-1H-pyrazol-3-yl)-phenyl]-ethanone

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Technology Process of 2-bromo-1-[4-(1-methyl-5-trifluoromethyl-1H-pyrazol-3-yl)-phenyl]-ethanone

There total 1 articles about 2-bromo-1-[4-(1-methyl-5-trifluoromethyl-1H-pyrazol-3-yl)-phenyl]-ethanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 930116-24-8
1-[4-(1-methyl-5-trifluoromethyl-1H-pyrazol-3-yl)-phenyl]-ethanone

: 929899-17-2
2-bromo-1-[4-(1-methyl-5-trifluoromethyl-1H-pyrazol-3-yl)-phenyl]-ethanone

Guidance literature:: With bromine; In diethyl ether; at 20 ℃; for 0.333333h;

Reference yield:

: 5-benzyloxymethyl-4-methyl-4H-[1,2,4]triazol-3-ylamine

: 929899-17-2
2-bromo-1-[4-(1-methyl-5-trifluoromethyl-1H-pyrazol-3-yl)-phenyl]-ethanone

: {3-methyl-5-[4-(1-methyl-5-trifluoromethyl-1H-pyrazol-3-yl)-phenyl]-3H-imidazo[1,2-b][1,2,4]triazol-2-yl}-methanol

Guidance literature:: 5-benzyloxymethyl-4-methyl-4H-[1,2,4]triazol-3-ylamine; 2-bromo-1-[4-(1-methyl-5-trifluoromethyl-1H-pyrazol-3-yl)-phenyl]-ethanone; In 1,2-dichloro-ethane; isopropyl alcohol; for 14h; Heating / reflux;

With acetic acid; at 170 ℃; for 36h; Sealed tube;

With sodium hydroxide; ammonium formate; palladium 10% on activated carbon; more than 3 stages;

Reference yield:

: 929899-17-2
2-bromo-1-[4-(1-methyl-5-trifluoromethyl-1H-pyrazol-3-yl)-phenyl]-ethanone

: 113293-71-3
(6-amino-3-pyridinyl)methanol

: 929898-44-2
{2-[4-(1-methyl-5-trifluoromethyl-1H-pyrazol-3-yl)-phenyl]-imidazo[1,2-a]pyridin-6-yl}-methanol

Guidance literature:: 2-bromo-1-[4-(1-methyl-5-trifluoromethyl-1H-pyrazol-3-yl)-phenyl]-ethanone; (6-amino-3-pyridinyl)methanol; In 1,2-dichloro-ethane; at 80 ℃; for 16h;

With sodium hydrogencarbonate; In 1,2-dichloro-ethane; at 80 ℃; for 24h;