(RS)-1-Benzenesulfonyl-2-(4-trifluoromethyl-phenyl)-pyrrolidine

Base Information

• Chemical Name: (RS)-1-Benzenesulfonyl-2-(4-trifluoromethyl-phenyl)-pyrrolidine
• CAS No.: 298690-50-3
• Molecular Formula: C₁₇H₁₆F₃NO₂S
• Molecular Weight: 355.381
• Mol file: 298690-50-3.mol

Synonyms:(RS)-1-Benzenesulfonyl-2-(4-trifluoromethyl-phenyl)-pyrrolidine

Chemical Property of (RS)-1-Benzenesulfonyl-2-(4-trifluoromethyl-phenyl)-pyrrolidine

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of (RS)-1-Benzenesulfonyl-2-(4-trifluoromethyl-phenyl)-pyrrolidine

There total 2 articles about (RS)-1-Benzenesulfonyl-2-(4-trifluoromethyl-phenyl)-pyrrolidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

C17H18F3NO2S → (RS)-1-Benzenesulfonyl-2-(4-trifluoromethyl-phenyl)-pyrrolidine (298690-50-3)

Guidance literature:

With iodine; (2-(N-methylbenzamido)phenyl)-l 3-iodanediyl diacetate; In dichloromethane; at 20 ℃; for 8h; Irradiation;

DOI:10.1002/adsc.202100316

Reference yield:

→ (RS)-1-Benzenesulfonyl-2-(4-trifluoromethyl-phenyl)-pyrrolidine (298690-50-3)

Guidance literature:

Reference yield: 91.0%

(RS)-1-Benzenesulfonyl-2-(4-trifluoromethyl-phenyl)-pyrrolidine (298690-50-3) → N-(4-oxo-4-(4-(trifluoromethyl)phenyl)butyl)benzenesulfonamide

Guidance literature:

With potassium peroxymonosulphate; hydrogen bromide; In nitromethane; water; at 0 - 20 ℃; for 24h;

DOI:10.1002/adsc.202001034