<2S-(2α,3aα,4β,7β,7aα)>-2-Methoxy-

Base Information

• Chemical Name: <2S-(2α,3aα,4β,7β,7aα)>-2-Methoxy-
• CAS No.: 113775-57-8
• Molecular Formula: C₁₃H₂₂O₂
• Molecular Weight: 210.316
• Mol file: 113775-57-8.mol

Synonyms:<2S-(2α,3aα,4β,7β,7aα)>-2-Methoxy-

Chemical Property of <2S-(2α,3aα,4β,7β,7aα)>-2-Methoxy-

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of <2S-(2α,3aα,4β,7β,7aα)>-2-Methoxy-

There total 11 articles about <2S-(2α,3aα,4β,7β,7aα)>-2-Methoxy- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

2-Amino-N-[(S)-2-(2,5-dimethoxy-phenyl)-2-((1R,2R,4S,6R,7R)-1,10,10-trimethyl-3-oxa-tricyclo[5.2.1.02,6]dec-4-yloxy)-ethyl]-acetamide → <2S-(2α,3aα,4β,7β,7aα)>-2-Methoxy- (113775-57-8) + (S)-2-Amino-N-<2-(2,5-dimethoxyphenyl)-2-hydroxyethyl>-acetamid-hydrochlorid (133163-28-7,3092-17-9,43218-56-0)

Guidance literature:

With hydrogenchloride; In methanol; diethyl ether; at 0 ℃; for 0.0166667h;

DOI:10.1007/bf00807396

Reference yield: 93.0%

2-Amino-N-[(R)-2-(2,5-dimethoxy-phenyl)-2-((1R,2R,4S,6R,7R)-1,10,10-trimethyl-3-oxa-tricyclo[5.2.1.02,6]dec-4-yloxy)-ethyl]-acetamide → <2S-(2α,3aα,4β,7β,7aα)>-2-Methoxy- (113775-57-8) + (R)-2-Amino-N-<2-(2,5-dimethoxyphenyl)-2-hydroxyethyl>-acetamid-hydrochlorid (133163-28-7,3092-17-9,43218-56-0)

Guidance literature:

With hydrogenchloride; In methanol; diethyl ether; at 0 ℃; for 0.0166667h;

DOI:10.1007/bf00807396

Reference yield: 92.0%

{[(R)-2-(2,5-Dimethoxy-phenyl)-2-((1R,2R,4S,6R,7R)-1,10,10-trimethyl-3-oxa-tricyclo[5.2.1.02,6]dec-4-yloxy)-ethylcarbamoyl]-methyl}-carbamic acid tert-butyl ester (177018-40-5) → <2S-(2α,3aα,4β,7β,7aα)>-2-Methoxy- (113775-57-8) + (R)-2-Amino-N-<2-(2,5-dimethoxyphenyl)-2-hydroxyethyl>-acetamid-hydrochlorid (133163-28-7,3092-17-9,43218-56-0)

Guidance literature:

With hydrogenchloride; In methanol; diethyl ether; at 40 ℃; for 0.0166667h;

DOI:10.1007/bf00807396

upstream raw materials:

<2R-(2α(2S*(2'S*,3a'R*,4'R*,7'R*,7a'R*),3Ξ*),3aα,4β,7β,7aα)>-2,4-Bis<(octahydro-7,8,8-trimethyl-4,7-methanobenzofuran-2-yl)oxy>-1,3-butandiol

<2R-(2α(2R*(2'S*,3a'R*,4'R*,7'R*,7a'R*),3R*),3aα,4β,7β,7aα)>-2,4-Bis<(octahydro-7,8,8-trimethyl-4,7-methanobenzofuran-2-yl)oxy>-1,3-butandiol

<2R-(2α(2R*(2'S*,3a'R*,4'R*,7'R*,7a'R*),3S*),3aα,4β,7β,7aα)>-2,4-Bis<(octahydro-7,8,8-trimethyl-4,7-methanobenzofuran-2-yl)oxy>-1,3-butandiol

{[(S)-2-(2,5-Dimethoxy-phenyl)-2-((1R,2R,4S,6R,7R)-1,10,10-trimethyl-3-oxa-tricyclo[5.2.1.0^2,6]dec-4-yloxy)-ethylcarbamoyl]-methyl}-carbamic acid tert-butyl ester

Downstream raw materials:

(2S,2'S-(2α,2'α,3aα,3a'α,4β,4'β,7β,7'β,7aα,7a'α))-2,2'-oxybis[octahydro-7,8,8-trimethyl-4,7-methanobenzofuran]