5'-O-(9-phenylxanthen-9-yl)thymidine-3'-(2-chlorophenyl) phosphate

Base Information

• Chemical Name: 5'-O-(9-phenylxanthen-9-yl)thymidine-3'-(2-chlorophenyl) phosphate
• CAS No.: 79258-44-9
• Molecular Formula: C₆H₁₅N*C₃₅H₃₀ClN₂O₉P
• Molecular Weight: 790.25
• Mol file: 79258-44-9.mol

Synonyms:5'-O-(9-phenylxanthen-9-yl)thymidine-3'-(2-chlorophenyl) phosphate

Chemical Property of 5'-O-(9-phenylxanthen-9-yl)thymidine-3'-(2-chlorophenyl) phosphate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 5'-O-(9-phenylxanthen-9-yl)thymidine-3'-(2-chlorophenyl) phosphate

There total 11 articles about 5'-O-(9-phenylxanthen-9-yl)thymidine-3'-(2-chlorophenyl) phosphate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

Phosphoric acid 2-chloro-phenyl ester methyl ester (2R,3S,5R)-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-2-(9-phenyl-9H-xanthen-9-yloxymethyl)-tetrahydro-furan-3-yl ester (84955-53-3) → 5'-O-(9-phenylxanthen-9-yl)thymidine-3'-(2-chlorophenyl) phosphate (79258-44-9)

Guidance literature:

With triethylamine; para-thiocresol; In acetonitrile; at 20 ℃; reaction with pyridine; the approximate times for half and complete reactions was measured;

DOI:10.1016/S0040-4039(00)81574-9

Reference yield:

Phosphoric acid benzyl ester 2-chloro-phenyl ester (2R,3S,5R)-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-2-(9-phenyl-9H-xanthen-9-yloxymethyl)-tetrahydro-furan-3-yl ester (84955-54-4) → 5'-O-(9-phenylxanthen-9-yl)thymidine-3'-(2-chlorophenyl) phosphate (79258-44-9)

Guidance literature:

With triethylamine; para-thiocresol; In acetonitrile; at 20 ℃; reaction with pyridine; the approximate times for half and complete reactions was measured;

DOI:10.1016/S0040-4039(00)81574-9

Reference yield:

Phosphoric acid 2-bromo-benzyl ester 2-chloro-phenyl ester (2R,3S,5R)-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-2-(9-phenyl-9H-xanthen-9-yloxymethyl)-tetrahydro-furan-3-yl ester (84981-50-0) → 5'-O-(9-phenylxanthen-9-yl)thymidine-3'-(2-chlorophenyl) phosphate (79258-44-9)

Guidance literature:

With triethylamine; para-thiocresol; In acetonitrile; at 20 ℃; reaction with pyridine; the approximate times for half and complete reactions was measured;

DOI:10.1016/S0040-4039(00)81574-9

upstream raw materials:

Phosphoric acid 2-chloro-phenyl ester methyl ester (2R,3S,5R)-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-2-(9-phenyl-9H-xanthen-9-yloxymethyl)-tetrahydro-furan-3-yl ester

Phosphoric acid benzyl ester 2-chloro-phenyl ester (2R,3S,5R)-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-2-(9-phenyl-9H-xanthen-9-yloxymethyl)-tetrahydro-furan-3-yl ester

Phosphoric acid 2-chloro-phenyl ester 2-methyl-benzyl ester (2R,3S,5R)-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-2-(9-phenyl-9H-xanthen-9-yloxymethyl)-tetrahydro-furan-3-yl ester

Phosphoric acid 2-bromo-benzyl ester 2-chloro-phenyl ester (2R,3S,5R)-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-2-(9-phenyl-9H-xanthen-9-yloxymethyl)-tetrahydro-furan-3-yl ester

Downstream raw materials:

Phosphoric acid 2-chloro-phenyl ester methyl ester (2R,3S,5R)-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-2-(9-phenyl-9H-xanthen-9-yloxymethyl)-tetrahydro-furan-3-yl ester

Phosphoric acid 2-chloro-phenyl ester (2R,3S,5R)-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-2-(9-phenyl-9H-xanthen-9-yloxymethyl)-tetrahydro-furan-3-yl ester 4-nitro-benzyl ester

Phosphoric acid 2-chloro-phenyl ester (2R,3S,5R)-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-2-(9-phenyl-9H-xanthen-9-yloxymethyl)-tetrahydro-furan-3-yl ester naphthalen-2-ylmethyl ester

Phosphoric acid 2-chloro-phenyl ester 2-methyl-benzyl ester (2R,3S,5R)-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-2-(9-phenyl-9H-xanthen-9-yloxymethyl)-tetrahydro-furan-3-yl ester