2-(3-phenylacetamido-4-thiol-(3R,4R)-azetidin-2-on-1-yl)-pivaloyloxymethyl acetate

Base Information

Chemical Name:2-(3-phenylacetamido-4-thiol-(3R,4R)-azetidin-2-on-1-yl)-pivaloyloxymethyl acetate
CAS No.:122691-75-2
Molecular Formula:C₁₉H₂₄N₂O₆S
Molecular Weight:408.475
Hs Code.:

Synonyms:2-(3-phenylacetamido-4-thiol-(3R,4R)-azetidin-2-on-1-yl)-pivaloyloxymethyl acetate

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 2-(3-phenylacetamido-4-thiol-(3R,4R)-azetidin-2-on-1-yl)-pivaloyloxymethyl acetate

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Technology Process of 2-(3-phenylacetamido-4-thiol-(3R,4R)-azetidin-2-on-1-yl)-pivaloyloxymethyl acetate

There total 3 articles about 2-(3-phenylacetamido-4-thiol-(3R,4R)-azetidin-2-on-1-yl)-pivaloyloxymethyl acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.0%

: 124166-14-9
2-<3-benzyl-6-oxo-2-thia-4,7-diaza-(1R,5R)-bicyclo-<3,2,0>-hept-3-en-7-yl>-pivaloyloxymethyl acetate

: 122691-75-2
2-(3-phenylacetamido-4-thiol-(3R,4R)-azetidin-2-on-1-yl)-pivaloyloxymethyl acetate

Guidance literature:: With hydrogenchloride; In N,N-dimethyl-formamide; for 1h; Ambient temperature;
DOI:10.1016/0223-5234(88)90100-6

Reference yield:

: 18997-19-8
Chloromethyl pivalate

: 122691-75-2
2-(3-phenylacetamido-4-thiol-(3R,4R)-azetidin-2-on-1-yl)-pivaloyloxymethyl acetate

Guidance literature:: Multi-step reaction with 2 steps

1: 65 percent

2: 76 percent / 1.2 N aq HCl / dimethylformamide / 1 h / Ambient temperature

With hydrogenchloride; In N,N-dimethyl-formamide;
DOI:10.1016/0223-5234(88)90100-6

Reference yield:

: 87996-80-3
2-<3-benzyl-6-oxo-2-thia-4,7-diaza-(1R,5R)-bicyclo-<3.2.0>-hept-3-en-7-yl>-acetic acid

: 122691-75-2
2-(3-phenylacetamido-4-thiol-(3R,4R)-azetidin-2-on-1-yl)-pivaloyloxymethyl acetate

Guidance literature:: Multi-step reaction with 2 steps

1: 65 percent

2: 76 percent / 1.2 N aq HCl / dimethylformamide / 1 h / Ambient temperature

With hydrogenchloride; In N,N-dimethyl-formamide;
DOI:10.1016/0223-5234(88)90100-6