(R)-(+)-1-phenyl-2-(1-pyrrolidinyl)-1-propanone hydrochloride

Base Information

• Chemical Name: (R)-(+)-1-phenyl-2-(1-pyrrolidinyl)-1-propanone hydrochloride
• CAS No.: 1215194-06-1
• Molecular Formula: C₁₃H₁₇NO*ClH
• Molecular Weight: 239.745
• Mol file: 1215194-06-1.mol

Synonyms:(R)-(+)-1-phenyl-2-(1-pyrrolidinyl)-1-propanone hydrochloride

Chemical Property of (R)-(+)-1-phenyl-2-(1-pyrrolidinyl)-1-propanone hydrochloride

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (R)-(+)-1-phenyl-2-(1-pyrrolidinyl)-1-propanone hydrochloride

There total 2 articles about (R)-(+)-1-phenyl-2-(1-pyrrolidinyl)-1-propanone hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

(1S,2R)-(+)-1-phenyl-2-(1-pyrrolidinyl)-1-propanol hydrochloride (1215194-05-0) → (R)-(+)-1-phenyl-2-(1-pyrrolidinyl)-1-propanone hydrochloride (1215194-06-1)

Guidance literature:

(1S,2R)-(+)-1-phenyl-2-(1-pyrrolidinyl)-1-propanol hydrochloride; With sodium dichromate; sulfuric acid; In water; at 15 - 20 ℃; for 12.3333h;

With sodium hydroxide; In water; toluene; at 20 ℃; pH=10.5;

With hydrogenchloride; In water; toluene; pH=2;

DOI:10.1016/j.tetasy.2009.11.019

Reference yield:

(1R,2R)-(+)-1-phenyl-2-(1-pyrrolidinyl)-1-propanol hydrochloride → (R)-(+)-1-phenyl-2-(1-pyrrolidinyl)-1-propanone hydrochloride (1215194-06-1)

Guidance literature:

(1R,2R)-(+)-1-phenyl-2-(1-pyrrolidinyl)-1-propanol hydrochloride; With sodium dichromate; sulfuric acid; In water; at 15 - 20 ℃; for 12.3333h;

With sodium hydroxide; In water; toluene; at 20 ℃; pH=10.5;

With hydrogenchloride; In water; toluene; pH=2;

DOI:10.1016/j.tetasy.2009.11.019

Reference yield:

(R)-(+)-1-phenyl-2-(1-pyrrolidinyl)-1-propanone hydrochloride (1215194-06-1) → (R)-(+)-1-phenyl-2-(1-pyrrolidinyl)-1-propanone (1215194-07-2)

Guidance literature:

With sodium hydroxide;

DOI:10.1016/j.tetasy.2009.11.019

upstream raw materials:

(1S,2R)-(+)-1-phenyl-2-(1-pyrrolidinyl)-1-propanol hydrochloride

Downstream raw materials:

(R)-(+)-1-phenyl-2-(1-pyrrolidinyl)-1-propanone