3-{3-[5-cyano-1-(2,4-dimethoxybenzyl)-3-(1-methyl-3-indolyl)-2-oxo-2,3-dihydro-1H-imidazol-4-yl]-1-indolyl}-propyl methanesulfonate

Base Information

Chemical Name:3-{3-[5-cyano-1-(2,4-dimethoxybenzyl)-3-(1-methyl-3-indolyl)-2-oxo-2,3-dihydro-1H-imidazol-4-yl]-1-indolyl}-propyl methanesulfonate
CAS No.:255371-92-7
Molecular Formula:C₃₄H₃₃N₅O₆S
Molecular Weight:639.732
Hs Code.:

Synonyms:3-{3-[5-cyano-1-(2,4-dimethoxybenzyl)-3-(1-methyl-3-indolyl)-2-oxo-2,3-dihydro-1H-imidazol-4-yl]-1-indolyl}-propyl methanesulfonate

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Chemical Property of 3-{3-[5-cyano-1-(2,4-dimethoxybenzyl)-3-(1-methyl-3-indolyl)-2-oxo-2,3-dihydro-1H-imidazol-4-yl]-1-indolyl}-propyl methanesulfonate

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Technology Process of 3-{3-[5-cyano-1-(2,4-dimethoxybenzyl)-3-(1-methyl-3-indolyl)-2-oxo-2,3-dihydro-1H-imidazol-4-yl]-1-indolyl}-propyl methanesulfonate

There total 1 articles about 3-{3-[5-cyano-1-(2,4-dimethoxybenzyl)-3-(1-methyl-3-indolyl)-2-oxo-2,3-dihydro-1H-imidazol-4-yl]-1-indolyl}-propyl methanesulfonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 59.0%

: 255371-91-6
4-cyano-3-(2,4-dimethoxybenzyl)-5-(3-indolyl)-1-(1-methyl-3-indolyl)-2,3-dihydroimidazol-2-one

: 15886-84-7
1,3-dimesyloxypropane

: 255371-92-7
3-{3-[5-cyano-1-(2,4-dimethoxybenzyl)-3-(1-methyl-3-indolyl)-2-oxo-2,3-dihydro-1H-imidazol-4-yl]-1-indolyl}-propyl methanesulfonate

Guidance literature:: With potassium carbonate; In DMF (N,N-dimethyl-formamide); at 70 ℃;

Reference yield: 72.0%

: 288-32-4
1H-imidazole

: 255371-92-7
3-{3-[5-cyano-1-(2,4-dimethoxybenzyl)-3-(1-methyl-3-indolyl)-2-oxo-2,3-dihydro-1H-imidazol-4-yl]-1-indolyl}-propyl methanesulfonate

: 255372-04-4
4-cyano-3-(2,4-dimethoxybenzyl)-5-[1-(3-{1-imidazolyl}-propyl)-3-indolyl]-1-(1-methyl-3-indolyl)-2,3-dihydroimidazol-2-one

Guidance literature:: 1H-imidazole; With sodium hydride; In DMF (N,N-dimethyl-formamide); at 20 ℃; for 0.5h;

3-{3-[5-cyano-1-(2,4-dimethoxybenzyl)-3-(1-methyl-3-indolyl)-2-oxo-2,3-dihydro-1H-imidazol-4-yl]-1-indolyl}-propyl methanesulfonate; In DMF (N,N-dimethyl-formamide); at 75 ℃; for 8h;