Phosphoric acid 2-chloro-4-nitro-phenyl ester 2-(2,2,2-trifluoro-ethylamino)-ethyl ester; hydrochloride

Base Information

• Chemical Name: Phosphoric acid 2-chloro-4-nitro-phenyl ester 2-(2,2,2-trifluoro-ethylamino)-ethyl ester; hydrochloride
• CAS No.: 73759-20-3
• Molecular Formula: C₁₀H₁₁ClF₃N₂O₆P*ClH
• Molecular Weight: 415.09
• Mol file: 73759-20-3.mol

Synonyms:Phosphoric acid 2-chloro-4-nitro-phenyl ester 2-(2,2,2-trifluoro-ethylamino)-ethyl ester; hydrochloride

Chemical Property of Phosphoric acid 2-chloro-4-nitro-phenyl ester 2-(2,2,2-trifluoro-ethylamino)-ethyl ester; hydrochloride

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

Useful:

Technology Process of Phosphoric acid 2-chloro-4-nitro-phenyl ester 2-(2,2,2-trifluoro-ethylamino)-ethyl ester; hydrochloride

There total 1 articles about Phosphoric acid 2-chloro-4-nitro-phenyl ester 2-(2,2,2-trifluoro-ethylamino)-ethyl ester; hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 20.0%

2-(2-Chloro-4-nitro-phenoxy)-3-(2,2,2-trifluoro-ethyl)-[1,3,2]oxazaphospholidine 2-oxide (73759-39-4) → Phosphoric acid 2-chloro-4-nitro-phenyl ester 2-(2,2,2-trifluoro-ethylamino)-ethyl ester; hydrochloride (73759-20-3)

Guidance literature:

With hydrogenchloride; water; In acetonitrile; for 1h;

DOI:10.1039/P29800000373

Reference yield:

Phosphoric acid 2-chloro-4-nitro-phenyl ester 2-(2,2,2-trifluoro-ethylamino)-ethyl ester; hydrochloride (73759-20-3) → 2-chloro-4-nitrophenol (619-08-9) + 2-Oxo-3-(2,2,2-trifluoro-ethyl)-2λ5-[1,3,2]oxazaphospholidin-2-ol anion

Guidance literature:

With potassium chloride; water; In methanol; at 35 ℃; for 0.25h; Rate constant; pH > 8; rate constant for the hydrolysis, k₀;

DOI:10.1039/P29800000373

upstream raw materials:

2-(2-Chloro-4-nitro-phenoxy)-3-(2,2,2-trifluoro-ethyl)-[1,3,2]oxazaphospholidine 2-oxide

Downstream raw materials:

2-chloro-4-nitrophenol