Technology Process of C25H34O5
There total 11 articles about C25H34O5 which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
C25H36O5;
With
oxalyl dichloride; dimethyl sulfoxide;
In
dichloromethane;
at -60 ℃;
for 1.5h;
With
N-ethyl-N,N-diisopropylamine;
In
dichloromethane;
at -78 - 0 ℃;
for 1.5h;
DOI:10.1021/jo200934w
- Guidance literature:
-
Multi-step reaction with 6 steps
1.1: sodium tetrahydroborate / methanol / 0.33 h / 0 - 25 °C
2.1: carbon tetrabromide; triphenylphosphine / dichloromethane / 0.67 h / 25 °C
3.1: toluene / 17 h / Reflux
4.1: n-butyllithium / tetrahydrofuran; cyclohexane / 1 h / -78 °C
4.2: 3 h / -78 - 25 °C
5.1: ammonium fluoride / methanol / 15 h / 60 °C
6.1: oxalyl dichloride; dimethyl sulfoxide / dichloromethane / 1.5 h / -60 °C
6.2: 1.5 h / -78 - 0 °C
With
ammonium fluoride; sodium tetrahydroborate; n-butyllithium; oxalyl dichloride; carbon tetrabromide; dimethyl sulfoxide; triphenylphosphine;
In
tetrahydrofuran; methanol; dichloromethane; cyclohexane; toluene;
2.1: Appel reaction / 4.2: Horner-Wadsworth-Emmons olefination / 6.1: Swern oxidation / 6.2: Swern oxidation;
DOI:10.1021/jo200934w
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: toluene / 17 h / Reflux
2.1: n-butyllithium / tetrahydrofuran; cyclohexane / 1 h / -78 °C
2.2: 3 h / -78 - 25 °C
3.1: ammonium fluoride / methanol / 15 h / 60 °C
4.1: oxalyl dichloride; dimethyl sulfoxide / dichloromethane / 1.5 h / -60 °C
4.2: 1.5 h / -78 - 0 °C
With
ammonium fluoride; n-butyllithium; oxalyl dichloride; dimethyl sulfoxide;
In
tetrahydrofuran; methanol; dichloromethane; cyclohexane; toluene;
2.2: Horner-Wadsworth-Emmons olefination / 4.1: Swern oxidation / 4.2: Swern oxidation;
DOI:10.1021/jo200934w
