2-Benzyloxycarbonyl-1-(t-butyloxycarbonyl)-1-(ethoxycarbonylmethyl)hydrazine

Base Information

• Chemical Name: 2-Benzyloxycarbonyl-1-(t-butyloxycarbonyl)-1-(ethoxycarbonylmethyl)hydrazine
• CAS No.: 258526-03-3
• Molecular Formula: C₁₇H₂₄N₂O₆
• Molecular Weight: 352.387
• Mol file: 258526-03-3.mol

Synonyms:2-Benzyloxycarbonyl-1-(t-butyloxycarbonyl)-1-(ethoxycarbonylmethyl)hydrazine

Chemical Property of 2-Benzyloxycarbonyl-1-(t-butyloxycarbonyl)-1-(ethoxycarbonylmethyl)hydrazine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-Benzyloxycarbonyl-1-(t-butyloxycarbonyl)-1-(ethoxycarbonylmethyl)hydrazine

There total 3 articles about 2-Benzyloxycarbonyl-1-(t-butyloxycarbonyl)-1-(ethoxycarbonylmethyl)hydrazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

C22H32N2O8 (202980-94-7) → 2-Benzyloxycarbonyl-1-(t-butyloxycarbonyl)-1-(ethoxycarbonylmethyl)hydrazine (258526-03-3)

Guidance literature:

With magnesium(II) perchlorate; In acetonitrile; at 50 ℃;

DOI:10.3891/acta.chem.scand.53-1127

Reference yield:

C21H27Cl3N2O8 (202980-90-3) → 2-Benzyloxycarbonyl-1-(t-butyloxycarbonyl)-1-(ethoxycarbonylmethyl)hydrazine (258526-03-3)

Guidance literature:

Multi-step reaction with 2 steps

1: 95 percent / NaOH (10 percent); TBAHS / acetonitrile

2: 99 percent / Mg(ClO₄)2 / acetonitrile / 50 °C

With sodium hydroxide; magnesium(II) perchlorate; tetra(n-butyl)ammonium hydrogensulfate; In acetonitrile; 1: Alkylation / 2: Elimination;

DOI:10.3891/acta.chem.scand.53-1127

Reference yield:

C18H26N2O6 (202980-91-4) → 2-Benzyloxycarbonyl-1-(t-butyloxycarbonyl)-1-(ethoxycarbonylmethyl)hydrazine (258526-03-3)

Guidance literature:

Multi-step reaction with 2 steps

1: aq. NaOH, n-Bu₄NHSO₄ / toluene / Ambient temperature

2: Mg(ClO₄)2 / acetonitrile / 0.25 h / 50 °C

With sodium hydroxide; magnesium(II) perchlorate; tetra(n-butyl)ammonium hydrogensulfate; In toluene; acetonitrile;

DOI:10.1016/S0040-4039(97)10634-7

upstream raw materials:

C₂₂H₃₂N₂O₈

C₂₁H₂₇Cl₃N₂O₈

C₁₈H₂₆N₂O₆

Downstream raw materials:

C₂₄H₃₀N₂O₆