1,4-Bis[3,4-dihydro-2(1H)-quinolinon-7-oxy]butane

Base Information

Chemical Name:1,4-Bis[3,4-dihydro-2(1H)-quinolinon-7-oxy]butane
CAS No.:882880-12-8
Molecular Formula:C₂₂H₂₄N₂O₄
Molecular Weight:380.444
Hs Code.:
UNII:FS6X5WDG7B
DSSTox Substance ID:DTXSID70470332
Nikkaji Number:J2.556.701C
Wikidata:Q82298401
Mol file:882880-12-8.mol

Synonyms:882880-12-8;1,4-Bis[3,4-dihydro-2(1H)-quinolinon-7-oxy]butane;7,7'-(Butane-1,4-diylbis(oxy))bis(3,4-dihydroquinolin-2(1H)-one);FS6X5WDG7B;2(1H)-Quinolinone,7,7'-[1,4-butanediylbis(oxy)]bis[3,4-dihydro-;Aripiprazole diquinoline butanediol;7-[4-[(2-oxo-3,4-dihydro-1H-quinolin-7-yl)oxy]butoxy]-3,4-dihydro-1H-quinolin-2-one;2(1H)-Quinolinone, 7,7'-(1,4-butanediylbis(oxy))bis(3,4-dihydro-;7,7'-(1,4-Butanediylbis(oxy))bis(3,4-dihydro-2(1H)-quinolinone);7-{4-[(2-oxo-1,2,3,4-tetrahydroquinolin-7-yl)oxy]butoxy}-1,2,3,4-tetrahydroquinolin-2-one;HYDKRRWQLHXDEN-UHFFFAOYSA-N;UNII-FS6X5WDG7B;SCHEMBL2842062;DTXSID70470332;7,7'-[1,4-Butanediylbis(oxy)]bis[3,4-dihydro-2(1H)-quinolinone;MFCD17018494;AKOS027379167;AC-28368;AS-71590;CS-0047323;FT-0663263;W15184;7,7'-[Butane-1,4-diylbis(oxy)]di(3,4-dihydroquinolin-2(1H)-one)

Suppliers and Price of 1,4-Bis[3,4-dihydro-2(1H)-quinolinon-7-oxy]butane

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
1,4-Bis[3,4-dihydro-2(1H)-quinolinon-7-oxy]butane
100mg
$ 175.00

TRC
1,4-Bis[3,4-dihydro-2(1H)-quinolinon-7-oxy]butane
1g
$ 1355.00

Chemenu
7,7''-(butane-1,4-diylbis(oxy))bis(3,4-dihydroquinolin-2(1H)-one) 97%
1g
$ 1571.00

Biosynth Carbosynth
1,4-Bis[3,4-dihydro-2(1H)-quinolinon-7-oxy]butane
1 g
$ 1700.00

Biosynth Carbosynth
1,4-Bis[3,4-dihydro-2(1H)-quinolinon-7-oxy]butane
50 mg
$ 140.00

Biosynth Carbosynth
1,4-Bis[3,4-dihydro-2(1H)-quinolinon-7-oxy]butane
250 mg
$ 495.00

Biosynth Carbosynth
1,4-Bis[3,4-dihydro-2(1H)-quinolinon-7-oxy]butane
100 mg
$ 240.00

Biosynth Carbosynth
1,4-Bis[3,4-dihydro-2(1H)-quinolinon-7-oxy]butane
500 mg
$ 940.00

American Custom Chemicals Corporation
ARIPIPRAZOLE IMPURITY D 95.00%
5MG
$ 498.34

AK Scientific
1,4-Bis[3,4-dihydro-2(1H)-quinolinon-7-oxy]butane
100mg
$ 374.00

Total 37 raw suppliers

Chemical Property of 1,4-Bis[3,4-dihydro-2(1H)-quinolinon-7-oxy]butane

Chemical Property:

Boiling Point:673.2±55.0 °C(Predicted)
PKA:14.11±0.20(Predicted)
PSA：76.66000
Density:1.226±0.06 g/cm3(Predicted)
LogP:3.97000
Storage Temp.:Refrigerator
Solubility.:DMSO (Slightly), Ethyl Acetate (Slightly, Heated), Methanol (Sparingly)
XLogP3:2.6
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:7
Exact Mass:380.17360725
Heavy Atom Count:28
Complexity:507

Purity/Quality:

99% ^*data from raw suppliers

1,4-Bis[3,4-dihydro-2(1H)-quinolinon-7-oxy]butane ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CC(=O)NC2=C1C=CC(=C2)OCCCCOC3=CC4=C(CCC(=O)N4)C=C3
Uses 1,4-Bis[3,4-dihydro-2(1H)-quinolinon-7-oxy]butane is an impurity found in the process for the preparation of Aripiprazole (A771000). Intermediate used in the process for the preparation of Aripiprazole (A771000).

Technology Process of 1,4-Bis[3,4-dihydro-2(1H)-quinolinon-7-oxy]butane

There total 9 articles about 1,4-Bis[3,4-dihydro-2(1H)-quinolinon-7-oxy]butane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.9%

: 22246-18-0
7-hydroxy-3,4-dihydro-2-(1H)-quinolinone

: 129722-34-5
7-(4-bromobutoxy)-3,4-dihydro-2(1H)-quinolinone

: 882880-12-8
7-(4-(2-oxo-1,2,3,4-tetrahydroquinolin-7-oxy)butoxy)-3,4-dihydroquinoline-2(1H)-one

Guidance literature:: With potassium carbonate; In N,N-dimethyl-formamide; at 80 ℃;
DOI:10.1021/acs.oprd.8b00438

Reference yield: 90.0%

: 119532-26-2,864512-47-0
1-(2,3-dichlorophenyl)-piperazine hydrochloride

: 120004-79-7
7-(4-chlorobutoxy)-3,4-dihydroquinoline-2(1H)-one

: 882880-12-8
7-(4-(2-oxo-1,2,3,4-tetrahydroquinolin-7-oxy)butoxy)-3,4-dihydroquinoline-2(1H)-one

: 129722-12-9
aripiprazole

Guidance literature:: With potassium carbonate; sodium iodide; tetrabutylammomium bromide; In acetonitrile; at 20 ℃; Product distribution / selectivity; Heating / reflux;