2β-aminomethyl-N-methyl-3β-p-tolyl-tropane

Base Information

• Chemical Name: 2β-aminomethyl-N-methyl-3β-p-tolyl-tropane
• CAS No.: 204004-77-3
• Molecular Formula: C₁₆H₂₄N₂
• Molecular Weight: 244.38
• Mol file: 204004-77-3.mol

Synonyms:2β-aminomethyl-N-methyl-3β-p-tolyl-tropane

Chemical Property of 2β-aminomethyl-N-methyl-3β-p-tolyl-tropane

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2β-aminomethyl-N-methyl-3β-p-tolyl-tropane

There total 3 articles about 2β-aminomethyl-N-methyl-3β-p-tolyl-tropane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

2β-phthalimidomethyl-N-methyl-3β-tolyl-tropane (440370-71-8) → 2β-aminomethyl-N-methyl-3β-p-tolyl-tropane (204004-77-3)

Guidance literature:

2β-phthalimidomethyl-N-methyl-3β-tolyl-tropane; With hydrazine; In ethanol; Heating;

With hydrogenchloride; In ethanol; Further stages.; Heating;

DOI:10.1021/jo010973x

Reference yield: 63.0%

2β-benzylaminomethyl-N-methyl-3β-p-tolyl-tropane (440370-72-9) → 2β-aminomethyl-N-methyl-3β-p-tolyl-tropane (204004-77-3)

Guidance literature:

With hydrogen; palladium on activated charcoal; In methanol; at 20 ℃; for 48h; under 760.051 Torr;

DOI:10.1021/jo010973x

Reference yield: 43.0%

3β-(4'-methylphenyl)tropane-2β-carboxamide (176698-57-0) → 2β-aminomethyl-N-methyl-3β-p-tolyl-tropane (204004-77-3)

Guidance literature:

3β-(4'-methylphenyl)tropane-2β-carboxamide; With borane; In tetrahydrofuran; for 1h; Heating;

With hydrogenchloride; In tetrahydrofuran; water; Further stages.; Heating;

DOI:10.1021/jo010973x

upstream raw materials:

3β-(4'-methylphenyl)tropane-2β-carboxamide

2β-benzylaminomethyl-N-methyl-3β-p-tolyl-tropane

2β-phthalimidomethyl-N-methyl-3β-tolyl-tropane

Downstream raw materials:

2β-phthalimidomethyl-N-methyl-3β-tolyl-tropane