1H-Pyrrolo[2,3-b]pyridine, 4-chloro-5-fluoro-1-[(4-methylphenyl)sulfonyl]-

Base Information

Chemical Name:1H-Pyrrolo[2,3-b]pyridine, 4-chloro-5-fluoro-1-[(4-methylphenyl)sulfonyl]-
CAS No.:882033-67-2
Molecular Formula:C14H10 Cl F N2 O2 S
Molecular Weight:324.763
Hs Code.:
Mol file:882033-67-2.mol

Synonyms:4-Chloro-5-fluoro-1-(4-tolylsulfonyl)-1H-pyrrolo[2,3-b]pyridine

Suppliers and Price of 1H-Pyrrolo[2,3-b]pyridine, 4-chloro-5-fluoro-1-[(4-methylphenyl)sulfonyl]-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 1 raw suppliers

Chemical Property of 1H-Pyrrolo[2,3-b]pyridine, 4-chloro-5-fluoro-1-[(4-methylphenyl)sulfonyl]-

Chemical Property:

Vapor Pressure:1.09E-09mmHg at 25°C
Refractive Index:1.653
Boiling Point:488.4°C at 760 mmHg
Flash Point:249.2°C
PSA：60.34000
Density:1.47g/cm³
LogP:4.45500

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 1H-Pyrrolo[2,3-b]pyridine, 4-chloro-5-fluoro-1-[(4-methylphenyl)sulfonyl]-

There total 2 articles about 1H-Pyrrolo[2,3-b]pyridine, 4-chloro-5-fluoro-1-[(4-methylphenyl)sulfonyl]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 882033-66-1
4-chloro-5-fluoro-1H-pyrrolo[2,3-b]pyridine

: 98-59-9
p-toluenesulfonyl chloride

: 882033-67-2
4-chloro-5-fluoro-1-(toluene-4-sulfonyl)-1H-pyrrolo[2,3-b]pyridine

Guidance literature:: With sodium hydroxide; tetra(n-butyl)ammonium hydrogensulfate; In water; toluene; at 20 ℃; for 24h;

Reference yield:

: 882033-67-2
4-chloro-5-fluoro-1-(toluene-4-sulfonyl)-1H-pyrrolo[2,3-b]pyridine

Guidance literature:

Reference yield:

: 882033-67-2
4-chloro-5-fluoro-1-(toluene-4-sulfonyl)-1H-pyrrolo[2,3-b]pyridine

: 1241675-23-9
1-(toluene-4-sulfonyl)-1H-2-iodo-4-chloro-5-fluoropyrrolo[2,3-b]pyridine

Guidance literature:: 4-chloro-5-fluoro-1-(toluene-4-sulfonyl)-1H-pyrrolo[2,3-b]pyridine; With tert.-butyl lithium; In tetrahydrofuran; at -78 ℃; for 0.5h;

With iodine; In tetrahydrofuran; at -78 ℃; for 2h;

With ammonium chloride; In tetrahydrofuran; water; at 0 ℃;