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Pyrimidine, 5-(1H-imidazol-5-yl)-2-methoxy-

Base Information Edit
  • Chemical Name:Pyrimidine, 5-(1H-imidazol-5-yl)-2-methoxy-
  • CAS No.:882032-65-7
  • Molecular Formula:C8H8N4O
  • Molecular Weight:176.178
  • Hs Code.:
  • Mol file:882032-65-7.mol
Pyrimidine,  5-(1H-imidazol-5-yl)-2-methoxy-

Synonyms:Pyrimidine,5-(1H-imidazol-4-yl)-2-methoxy- (9CI)

Suppliers and Price of Pyrimidine, 5-(1H-imidazol-5-yl)-2-methoxy-
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Business phase:
The product has achieved commercial mass production*data from LookChem market partment
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Chemical Property of Pyrimidine, 5-(1H-imidazol-5-yl)-2-methoxy- Edit
Chemical Property:
  • PSA:63.69000 
  • LogP:0.87530 
Purity/Quality:
Safty Information:
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MSDS Files:

SDS file from LookChem

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Technology Process of Pyrimidine, 5-(1H-imidazol-5-yl)-2-methoxy-

There total 2 articles about Pyrimidine, 5-(1H-imidazol-5-yl)-2-methoxy- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:
Guidance literature:
With hydrogenchloride; In ethanol; at 20 ℃;
DOI:10.1021/jm051157a
Guidance literature:
Multi-step reaction with 2 steps
1.1: EtMgBr / tetrahydrofuran / 1.5 h / 20 °C
1.2: ZnCl2 / tetrahydrofuran / 1.5 h
1.3: tetrakis(triphenylphosphine)palladium / tetrahydrofuran / Heating
2.1: aq. HCl / ethanol / 20 °C
With hydrogenchloride; ethylmagnesium bromide; In tetrahydrofuran; ethanol; 1.3: Negishi reaction;
DOI:10.1021/jm051157a
Guidance literature:
Multi-step reaction with 3 steps
1: 30 percent / K2CO3 / dimethylformamide / 36 h / 20 °C
2: 95 percent / hydrazine / ethanol / 15 h / Heating
3: acetonitrile; H2O / 12 h
With potassium carbonate; hydrazine; In ethanol; water; N,N-dimethyl-formamide; acetonitrile;
DOI:10.1021/jm051157a
upstream raw materials:

5-bromo-2-methoxypyrimidine

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