PIPERIDIN-4-YL-(2-TRIFLUOROMETHYL-PHENYL)-METHANONE HYDROCHLORIDE

Base Information

Chemical Name:PIPERIDIN-4-YL-(2-TRIFLUOROMETHYL-PHENYL)-METHANONE HYDROCHLORIDE
CAS No.:881391-41-9
Molecular Formula:C13H14 F3 N O
Molecular Weight:257.255
Hs Code.:
Mol file:881391-41-9.mol

Synonyms:(Piperidin-4-yl)(2-trifluoromethylphenyl)methanone

Suppliers and Price of PIPERIDIN-4-YL-(2-TRIFLUOROMETHYL-PHENYL)-METHANONE HYDROCHLORIDE

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 9 raw suppliers

Chemical Property of PIPERIDIN-4-YL-(2-TRIFLUOROMETHYL-PHENYL)-METHANONE HYDROCHLORIDE

Chemical Property:

PSA：29.10000
LogP:4.01850

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of PIPERIDIN-4-YL-(2-TRIFLUOROMETHYL-PHENYL)-METHANONE HYDROCHLORIDE

There total 1 articles about PIPERIDIN-4-YL-(2-TRIFLUOROMETHYL-PHENYL)-METHANONE HYDROCHLORIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 55.0%

: 881391-42-0
4-(2-trifluoromethylbenzoyl)piperidine-1-carboxylic acid tert-butyl ester

: 881391-41-9
piperidin-4-yl[2-(trifluoromethyl)phenyl]methanone

Guidance literature:: With trifluoroacetic acid; In dichloromethane; at 20 ℃;

Reference yield:

: 881391-41-9
piperidin-4-yl[2-(trifluoromethyl)phenyl]methanone

: 1241897-97-1
ethyl [5-(2-chloropyrimidin-5-yl)-2H-tetrazol-2-yl]acetate

: ethyl [5-(2-{4-[2-(trifluoromethyl)benzoyl]piperidin-1-yl}pyrimidin-5-yl)-2H-tetrazol-2-yl]acetate

Guidance literature:: With potassium carbonate; In 1,4-dioxane; at 70 ℃; for 18h;

Reference yield:

: 881391-41-9
piperidin-4-yl[2-(trifluoromethyl)phenyl]methanone

: 1241897-97-1
ethyl [5-(2-chloropyrimidin-5-yl)-2H-tetrazol-2-yl]acetate

: 1241896-60-5
[5-(2-{4-[2-(trifluoromethyl)benzoyl]piperidin-1-yl}pyrimidin-5-yl)-2H-tetrazol-2-yl]acetic acid

Guidance literature:: Multi-step reaction with 2 steps

1: potassium carbonate / 1,4-dioxane; dimethyl sulfoxide / 18 h / 70 °C

2: water; lithium hydroxide / 1,4-dioxane; methanol / 16 h / 20 °C

With water; potassium carbonate; lithium hydroxide; In 1,4-dioxane; methanol; dimethyl sulfoxide;